β-blockers is a vast group of antiarrhythmic drugs which differ in their pharmacokinetic and
chemical properties. Some of them block β-adrenergic receptors selectively while the others …

Over the last years, repurposed agents have provided growing evidence of fast
implementation in oncology treatment such as certain antimalarial, anthelmintic, antibiotics …

Osteosarcoma is still associated with limited response to standard-of-care therapy and
alarmingly elevated mortality rates, especially in low-and middle-income countries. Despite …

Background: Cervical cancer (CC) is characterized by genomic alterations in DNA repair
genes, which could favour treatment with agents causing DNA double-strand breaks (DSBs) …

Studies published in the last two decades have clearly demonstrated that the nervous
system plays a significant role in carcinogenesis, the progression of cancer, and the …

The V600E mutation in BRAF is associated with increased phosphorylation of Erk1/2 and
high sensitivity to BRAFi/MEKi combination in metastatic melanoma. In very few patients, a …

Angiosarcoma is a rare cancer of blood vessel–forming cells with a high patient mortality
and few treatment options. Although chemotherapy often produces initial clinical responses …

Human angiosarcoma and canine hemangiosarcoma reveal similarities not only in their
aggressive clinical behaviour, but especially in molecular landscape and genetic alterations …

Simple Summary Emerging evidence has suggested that cancer-derived extracellular
vesicles (EVs) have a crucial role in mediating directional metastasis to the peritoneal …

Stress hormones are believed to skew the CD4 T‐cell differentiation towards a Th2
response via a T‐cell‐extrinsic mechanism. Using isolated primary human naïve and …