Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity
R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …
[HTML][HTML] Progress report on new antiepileptic drugs: a summary of the Eleventh Eilat Conference (EILAT XI)
M Bialer, SI Johannessen, RH Levy, E Perucca… - Epilepsy research, 2013 - Elsevier
The Eleventh Eilat Conference on New Antiepileptic Drugs (AEDs)-EILAT XI, took place in
Eilat, Israel from the 6th to 10th of May 2012. About 100 basic scientists, clinical …
Eilat, Israel from the 6th to 10th of May 2012. About 100 basic scientists, clinical …
The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease
R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …
[HTML][HTML] Galanin receptors and ligands
KEB Webling, J Runesson, T Bartfai… - Frontiers in …, 2012 - frontiersin.org
The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …
[HTML][HTML] Immunomodulatory role of neuropeptides in the cornea
The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …
leukocyte populations make it an ideal tissue to study interactions between the nervous and …
Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity
J. Neurochem.(2010) 113, 649–660. Abstract Degeneration of locus coeruleus (LC)
noradrenergic forebrain projection neurons is an early feature of Alzheimer's disease. The …
noradrenergic forebrain projection neurons is an early feature of Alzheimer's disease. The …
Brain galanin system genes interact with life stresses in depression-related phenotypes
Galanin is a stress-inducible neuropeptide and cotransmitter in serotonin and
norepinephrine neurons with a possible role in stress-related disorders. Here we report that …
norepinephrine neurons with a possible role in stress-related disorders. Here we report that …
Structural insights into galanin receptor signaling
W Jiang, S Zheng - Proceedings of the National Academy of …, 2022 - National Acad Sciences
Galanin is a biologically active neuropeptide, and functions through three distinct G protein–
coupled receptors (GPCRs), namely GALR1, GALR2, and GALR3. GALR signaling plays …
coupled receptors (GPCRs), namely GALR1, GALR2, and GALR3. GALR signaling plays …
[HTML][HTML] Molecular and cellular mechanisms of perineural invasion in oral squamous cell carcinoma: potential targets for therapeutic intervention
CI Misztal, C Green, C Mei, R Bhatia, JM Velez Torres… - Cancers, 2021 - mdpi.com
Simple Summary Squamous cell carcinoma is the most common type of oral cavity cancer. It
can spread along and invade nerves in a process called perineural invasion. Perineural …
can spread along and invade nerves in a process called perineural invasion. Perineural …
[HTML][HTML] Development of spexin-based human galanin receptor type II-specific agonists with increased stability in serum and anxiolytic effect in mice
A Reyes-Alcaraz, YN Lee, GH Son, NH Kim, DK Kim… - Scientific reports, 2016 - nature.com
The novel neuropeptide spexin (SPX) was discovered to activate galanin receptor 2
(GALR2) and 3 (GALR3) but not galanin receptor 1 (GALR1). Although GALR2 is known to …
(GALR2) and 3 (GALR3) but not galanin receptor 1 (GALR1). Although GALR2 is known to …