Ferroptosis is a form of regulated cell death characterized by iron-dependent lipid
peroxidation. This process contributes to cellular and tissue damage in various human …

Due to the urgent demand for more anti-cancer methods, the new applications of metal ions
in cancer have attracted increasing attention. Especially the three kinds of the new mode of …

Background Bladder cancer (BLCA) is the most common malignancy of the urinary tract. On
the other hand, disulfidptosis, a mechanism of disulfide stress-induced cell death, is closely …

Phospholipids containing a single polyunsaturated fatty acyl tail (PL-PUFA 1 s) are
considered the driving force behind ferroptosis, whereas phospholipids with diacyl-PUFA …

Although transcription factor CCAAT-enhancer binding protein α (C/EBPα) is critical for
normal and leukemic differentiation, its role in cell and metabolic homeostasis is largely …

The microenvironment in solid tumors drives the fate of cancer cells to ferroptosis, yet the
underlying mechanism remains incompletely understood. Herein, we report a metal-free …

Myeloid immune cells (MICs) are potent innate immune cells serving as first responders to
invading pathogens and internal changes to cellular homeostasis. Cancer is a stage of …

Glioblastoma (GBM) is the most lethal primary brain tumor. With limited therapeutic options,
novel therapies are desperately needed. Recent studies have shown that GBM acquires …

There are limited options for patients who develop liver metastasis from colorectal cancer
(CRC), the leading cause of cancer-related mortality worldwide. Emerging evidence has …

Imatinib (IM) has significantly improved the prognosis of gastrointestinal stromal tumor
(GIST) patients, but some patients still have primary resistance to IM, and approximately half …