Duchenne muscular dystrophy (DMD) is caused by the lack of functional dystrophin protein.
Improvements in patient care and disease management have slowed down disease …

The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

Duchenne muscular dystrophy (DMD) is a severe, progressive, and incurable X-linked
disorder caused by mutations in the dystrophin gene. Patients with DMD have an absence of …

Muscle wasting is associated with a wide range of catabolic diseases. This debilitating loss
of muscle mass and functional capacity reduces the quality of life and increases the risks of …

The transforming growth factor-beta (TGF-β) superfamily consists of a variety of cytokines
expressed in many different cell types including skeletal muscle. Members of this …

Myostatin inhibitors as therapies for muscle wasting associa... : Current Opinion in Supportive
and Palliative Care Myostatin inhibitors as therapies for muscle wasting associated with cancer …

Skeletal muscle can undergo a regenerative process in response to injury or disease to
preserve muscle mass and function, which are critically influenced by cellular stress …

Myostatin inhibition therapy has held much promise for the treatment of muscle wasting
disorders. This is particularly true for the fatal myopathy, Duchenne Muscular Dystrophy …

Fibro-adipogenic progenitors (FAPs) are key regulators of skeletal muscle regeneration and
homeostasis. However, dysregulation of these cells leads to fibro-fatty infiltration across …

A significant proportion of heart failure patients develop skeletal muscle wasting and cardiac
cachexia, which is associated with a very poor prognosis. Recently, myostatin, a cytokine …