Parental environmental factors, including diet, body composition, metabolism, and stress,
affect the health and chronic disease risk of people throughout their lives, as captured in the …

One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that
include the methionine and folate cycles that are central to cellular function, providing 1C …

The association between poor paternal diet, perturbed embryonic development, and adult
offspring ill health represents a new focus for the Developmental Origins of Health and …

It is well established that the maternal diet during the periconceptional period affects the
progeny's health. A growing body of evidence suggests that the paternal diet also influences …

BACKGROUND According to the Developmental Origins of Health and Disease (DOHaD)
hypothesis, environmental changes taking place during early maturational periods may alter …

Our efforts to understand the developmental origins of birth defects and disease have
primarily focused on maternal exposures and intrauterine stressors. Recently, research into …

The concept that a father's wellbeing at the time of conception influences the development
and long-term health of his offspring is now well established. However, the mechanisms …

The concept emerging from Professor David Barker's seminal research on the
developmental origins of later-life disease has progressed in many directions since it was …

Assisted reproductive techniques (ART) and parental nutritional status have profound effects
on embryonic/fetal and placental development, which are probably mediated via …

Paternal programming is the concept that the environmental signals from the sire's
experiences leading up to mating can alter semen and ultimately affect the phenotype of …