The microbiota-gut-brain axis has emerged as a novel target in depression, a disorder with
low treatment efficacy. However, the field is dominated by underpowered studies focusing …

Growing evidence implicates the gut microbiome in cognition. Viruses, the most abundant
life entities on the planet, are a commonly overlooked component of the gut virome …

The mushroom body (MB) is a computational center in the Drosophila brain. The intricate
neural circuits of the mushroom body enable it to store associative memories and process …

Intellectual disability (ID) and autism spectrum disorders (ASD) are frequently co-occurring
neurodevelopmental disorders and affect 2-3% of the population. Rapid advances in exome …

Abstract Peroxiredoxin 3 (PRDX3) belongs to a superfamily of peroxidases that function as
protective antioxidant enzymes. Among the six isoforms (PRDX1–PRDX6), PRDX3 is the …

The gut microbiota contributes to the pathophysiology of non-alcoholic fatty liver disease
(NAFLD). Histidine is a key energy source for the microbiota, scavenging it from the host. Its …

Recent advances in the genetics of neurodevelopmental disorders (NDDs) have identified
the transcription factor FOXP2 as one of numerous risk genes, eg in autism spectrum …

Brain organoids are proving to be physiologically relevant models for studying human brain
development in terms of temporal transcriptional signature recapitulation, dynamic …

Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental
disorder resulting from the interaction between genetic and environmental risk factors. It is …

Habituation is the most fundamental form of learning. As a firewall that protects our brain
from sensory overload, it is indispensable for cognitive processes. Studies in humans and …