Particulate vaccines: on the quest for optimal delivery and immune response
ML De Temmerman, J Rejman, J Demeester… - Drug discovery today, 2011 - Elsevier
Subunit vaccines offer a safer alternative to traditional organism-based vaccines, but their
immunogenicity is impaired. This hurdle might be overcome by the use of micro-and …
immunogenicity is impaired. This hurdle might be overcome by the use of micro-and …
Biodegradable poly (lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens
Injectable biodegradable polymeric particles (usually microspheres) represent an exciting
approach to control the release of vaccine antigens to reduce the number of doses in the …
approach to control the release of vaccine antigens to reduce the number of doses in the …
[图书][B] Handbook of encapsulation and controlled release
M Mishra - 2015 - books.google.com
The field of encapsulation, especially microencapsulation, is a rapidly growing area of
research and product development. The Handbook of Encapsulation and Controlled …
research and product development. The Handbook of Encapsulation and Controlled …
Particulate formulations for the delivery of poly (I: C) as vaccine adjuvant
AM Hafner, B Corthésy, HP Merkle - Advanced drug delivery reviews, 2013 - Elsevier
Current research and development of antigens for vaccination often center on purified
recombinant proteins, viral subunits, synthetic oligopeptides or oligosaccharides, most of …
recombinant proteins, viral subunits, synthetic oligopeptides or oligosaccharides, most of …
Vaccine adjuvants: current challenges and future approaches
JH Wilson-Welder, MP Torres, MJ Kipper… - Journal of …, 2009 - Elsevier
For humans, companion animals, and food producing animals, vaccination has been touted
as the most successful medical intervention for the prevention of disease in the twentieth …
as the most successful medical intervention for the prevention of disease in the twentieth …
Micro and nanoparticle‐based delivery systems for vaccine immunotherapy: an immunological and materials perspective
J Leleux, K Roy - Advanced healthcare materials, 2013 - Wiley Online Library
The development and widespread application of vaccines has been one of the most
significant achievements of modern medicine. Vaccines have not only been instrumental in …
significant achievements of modern medicine. Vaccines have not only been instrumental in …
Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response
V Kanchan, AK Panda - Biomaterials, 2007 - Elsevier
Size of the polymeric particulate antigen delivery system and its interactions with antigen-
presenting cells (APCs) influence the immune response both qualitatively and quantitatively …
presenting cells (APCs) influence the immune response both qualitatively and quantitatively …
Composite dissolving microneedles for coordinated control of antigen and adjuvant delivery kinetics in transcutaneous vaccination
PC DeMuth, WF Garcia‐Beltran… - Advanced functional …, 2013 - Wiley Online Library
Transcutaneous administration has the potential to improve therapeutics delivery, providing
an approach that is safer and more convenient than traditional alternatives, while offering …
an approach that is safer and more convenient than traditional alternatives, while offering …
[HTML][HTML] Harnessing dendritic cells for poly (D, L-lactide-co-glycolide) microspheres (PLGA MS)—Mediated anti-tumor therapy
J Koerner, D Horvath, M Groettrup - Frontiers in immunology, 2019 - frontiersin.org
With emerging success in fighting off cancer, chronic infections, and autoimmune diseases,
immunotherapy has become a promising therapeutic approach compared to conventional …
immunotherapy has become a promising therapeutic approach compared to conventional …
Single-injection vaccines: Progress, challenges, and opportunities
Currently, vaccination is the most efficient and cost-effective medical treatment for infectious
diseases; however, each year 10 million infants remain underimmunized due to current …
diseases; however, each year 10 million infants remain underimmunized due to current …