Alzheimer Disease (AD) is a pathology that causes millions of deaths every year and it also
generates severe economic consequences for families and public health systems. Oxidative …

Blood-brain barrier (BBB) damage is a critical neurovascular complication of diabetes
mellitus that adversely affects the CNS health and function. Previously, we showed the …

The global prevalence of diabetes mellitus was 8.4% of the total population in 2017 and is
expected to reach approximately 10% in 2045. 1 The lifetime risk of developing diabetes is …

Background Hyperglycemia has shown a negative association with cognitive dysfunction.
We analyzed patients with high preoperative blood glucose level and hemoglobin A 1c (HbA …

Although it is feared that diabetes-induced cognitive impairment (DCI) will become a major
clinical problem worldwide in the future, its detailed pathological mechanism is not well …

INTRODUCTION This study examined the relationship between blood‐brain‐barrier
permeability (BBBp), measured by cerebrospinal fluid/serum albumin ratio (QAlb), and …

Dementia is one of the greatest public health concerns for the modern aging world. Over the
last decade, most researchers developing new therapeutic strategies for dementia have …

Rationale Frontotemporal dementia (FTD) and dementia with Lewy bodies (DLB) are two
common forms of neurodegenerative dementia, subsequent to Alzheimer's disease (AD). AD …

The brain is the most vulnerable organ to glucose fluctuations, as well as inflammation.
Considering that cognitive impairment might occur at the early stage of diabetes, it is very …

Aim The aim of this observational study was to investigate relationships between
physiological levels of glucometabolic biomarkers and cognitive test results in a population …