Background Cancer development and tumor immune microenvironment remodeling are
closely linked to pyroptosis and inflammasome activation. However, little information is …

Inflammasomes are protein scaffolds required for the activation of caspase-1 and the
subsequent release of interleukin (IL)-1β, IL-18, and danger signals, as well as the induction …

Complete hydatidiform mole (HM) is a gestational trophoblastic disease resulting in
hyperproliferation of trophoblast cells and absence of embryo development. Mutations in the …

Mycobacterium bovis (M. bovis), the most common pathogens of tuberculosis (TB), is virulent
to human and cattle, and transmission between cattle and humans warrants reconsideration …

Background Colorectal cancer (CRC) is one of the most common malignancies, and
pyroptosis exerts an immunoregulatory role in CRC. Although the location of the primary …

Background Nucleotide-binding oligomerization domain (NACHT), leucine rich repeat (LRR)
and pyrin domain (PYD) 7 containing protein, NLRP7, is a member of the NLR family which …

Preterm prelabor ruptures of fetal membranes (pPROM) are a pregnancy complication
responsible for 30% of all preterm births. This pathology currently appears more as a …

Macrophage polarization, regulated appropriately, may play important roles in successful
pregnancy. In the face of the vital roles of decidua macrophages in pregnancy, it is …

Mycobacterium bovis, the causative agent of tuberculosis in cattle and humans, infects host
macrophages and induces endoplasmic reticulum stress (ERS), mitochondrial damage, and …

Objective Bovine tuberculosis (bTB) is a chronic respiratory infectious disease of domestic
livestock caused by intracellular Mycobacterium bovis infection, which causes~ $3 billion in …