Abstract The 2022 World Health Organization (WHO) classification of the urinary and male
genital tumors was recently published by the International Agency for Research on Cancer …

Context To improve the prognosis of upper tract urothelial carcinoma (UTUC), clinicians
have used neoadjuvant chemotherapy (NAC) or adjuvant chemotherapy (AC) before or after …

Background The role of adjuvant treatment in high-risk muscle-invasive urothelial carcinoma
after radical surgery is not clear. Methods In a phase 3, multicenter, double-blind …

The latest research confirms that cytotoxic lymphocytes rely on pyroptosis to kill tumor cells,
suggesting that pyroptosis plays a vital role in immune response. However, the influence of …

Aging is related to cancer, and an increasing incidence of malignant tumors among the older
population is observed [1]. Urinary tumors, such as prostate cancer, bladder cancer (BC) …

Bladder cancer (BC) is characterized by high incidence and recurrence rates together with
genomic instability and elevated mutation degree. Currently, cystoscopy combined with …

Background Optimal patient selection for neoadjuvant chemotherapy prior to surgical
extirpation is limited by the inaccuracy of contemporary clinical staging methods in high-risk …

Precision medicine has transformed the way urothelial carcinoma is managed. However,
current practices are limited by the availability of tissue samples for genomic profiling and …

Drug resistance contributes to poor therapeutic response in urothelial carcinoma (UC).
Metabolomic analysis suggested metabolic reprogramming in gemcitabine‐resistant …

Purpose: Our goal was to evaluate long-term safety and durability of response to UGN-101,
a mitomycin-containing reverse thermal gel, as primary chemoablative treatment for low …