A substrate‐based ontology for human solute carriers
E Meixner, U Goldmann, V Sedlyarov… - Molecular Systems …, 2020 - embopress.org
Solute carriers (SLCs) are the largest family of transmembrane transporters in the human
genome with more than 400 members. Despite the fact that SLCs mediate critical biological …
genome with more than 400 members. Despite the fact that SLCs mediate critical biological …
Molecular pathways: metabolic control of histone methylation and gene expression in cancer
TQ Tran, XH Lowman, M Kong - Clinical Cancer Research, 2017 - AACR
Epigenetic alterations contribute to tumor development, progression, and therapeutic
response. Many epigenetic enzymes use metabolic intermediates as cofactors to modify …
response. Many epigenetic enzymes use metabolic intermediates as cofactors to modify …
DNA‐methylation‐mediated silencing of miR‐7‐5p promotes gastric cancer stem cell invasion via increasing Smo and Hes1
L Xin, L Liu, C Liu, LQ Zhou, Q Zhou… - Journal of Cellular …, 2020 - Wiley Online Library
Cancer stem cells are undifferentiated cancer cells that have self‐renewal ability, a high
tumorigenic activity, and a multilineage differentiation potential. MicroRNAs play a critical …
tumorigenic activity, and a multilineage differentiation potential. MicroRNAs play a critical …
Association of sulfur amino acid consumption with cardiometabolic risk factors: cross-sectional findings from NHANES III
Abstract Background An average adult American consumes sulfur amino acids (SAA) at
levels far above the Estimated Average Requirement (EAR) and recent preclinical data …
levels far above the Estimated Average Requirement (EAR) and recent preclinical data …
Interactions of cisplatin with non-DNA targets and their influence on anticancer activity and drug toxicity: the complex world of the platinum complex
R Mezencev - Current cancer drug targets, 2014 - ingentaconnect.com
Since the discovery of its anticancer activity in 1970s, cisplatin and its analogs have become
widely used in clinical practice, being administered to 40-80% of patients undergoing …
widely used in clinical practice, being administered to 40-80% of patients undergoing …
99mTc-methionine gold nanoparticles as a promising biomaterial for enhanced tumor imaging
Methionine-gold nanoparticles (MGNs) was synthesized by conjugating methionine via
dithiocarbamate linkage to gold nanoparticles (GNPs), prepared simultaneously by one pot …
dithiocarbamate linkage to gold nanoparticles (GNPs), prepared simultaneously by one pot …
A metabolomic approach to identifying platinum resistance in ovarian cancer
LM Poisson, A Munkarah, H Madi, I Datta… - Journal of ovarian …, 2015 - Springer
Background Acquisition of metabolic alterations has been shown to be essential for the
unremitting growth of cancer, yet the relation of such alterations to chemosensitivity has not …
unremitting growth of cancer, yet the relation of such alterations to chemosensitivity has not …
Disease prevention and delayed aging by dietary sulfur amino acid restriction: translational implications
Z Dong, R Sinha, JP Richie Jr - … of the New York Academy of …, 2018 - Wiley Online Library
Sulfur amino acids (SAAs) play numerous critical roles in metabolism and overall health
maintenance. Preclinical studies have demonstrated that SAA‐restricted diets have many …
maintenance. Preclinical studies have demonstrated that SAA‐restricted diets have many …
Dietary methionine restriction improves gastrocnemius muscle glucose metabolism through improved insulin secretion and H19/IRS-1/akt pathway in middle-aged …
C Feng, Y Jiang, G Wu, Y Shi, Y Ge, B Li… - Journal of Agricultural …, 2023 - ACS Publications
Methionine restriction (MR) improves glucose metabolism. In skeletal muscle, H19 is a key
regulator of insulin sensitivity and glucose metabolism. Therefore, this study aims to reveal …
regulator of insulin sensitivity and glucose metabolism. Therefore, this study aims to reveal …
Peptides derived from fermented soybean meal suppresses intestinal inflammation and enhances epithelial barrier function in piglets
Y Zhang, S Chen, X Zong, C Wang, C Shi… - Food and Agricultural …, 2020 - Taylor & Francis
This study was to investigate the effects of peptides derived from fermented soybean meal
(FSP) on intestinal inflammation and epithelial barrier function of the piglets. Compared to …
(FSP) on intestinal inflammation and epithelial barrier function of the piglets. Compared to …