Mobile genetic element flexibility as an underlying principle to bacterial evolution
AJ Weisberg, JH Chang - Annual Review of Microbiology, 2023 - annualreviews.org
Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …
ecosystem health. Here, we use a framework of a hierarchical and modular system that …
Defense systems are pervasive across chromosomally integrated mobile genetic elements and are inversely correlated to virulence and antimicrobial resistance
J Botelho - Nucleic acids research, 2023 - academic.oup.com
Mobile genetic elements (MGEs) are key promoters of microbial evolution. These elements
can be located extrachromosomally or integrated into the chromosome. Well-known …
can be located extrachromosomally or integrated into the chromosome. Well-known …
[HTML][HTML] Genomic and metabolic versatility of Pseudomonas aeruginosa contributes to its inter-kingdom transmission and survival
S Ambreetha, D Zincke… - Journal of Medical …, 2024 - microbiologyresearch.org
Pseudomonas aeruginosa is one of the most versatile bacteria with renowned pathogenicity
and extensive drug resistance. The diverse habitats of this bacterium include fresh, saline …
and extensive drug resistance. The diverse habitats of this bacterium include fresh, saline …
A widespread bacterial mobile genetic element encodes weapons against phages, bacteria, and eukaryotes
Bacteria are found in ongoing conflicts with rivals and predators, which lead to an
evolutionary arms race and the development of innate and adaptive immune systems …
evolutionary arms race and the development of innate and adaptive immune systems …
[HTML][HTML] A VirB4 ATPase of the mobile accessory genome orchestrates core genome-encoded features of physiology, metabolism, and virulence of Pseudomonas …
L Wiehlmann, J Klockgether… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
Pseudomonas aeruginosa TBCF10839 is a highly virulent strain that can persist and
replicate in human neutrophils. Screening of a signature-tagged mutagenesis (STM) …
replicate in human neutrophils. Screening of a signature-tagged mutagenesis (STM) …
Diversity and evolution of an abundant ICEclc family of integrative and conjugative elements in Pseudomonas aeruginosa
V Benigno, N Carraro, G Sarton-Lohéac… - Msphere, 2023 - Am Soc Microbiol
Integrative and conjugative elements (ICEs) are widespread autonomous mobile DNA
elements, containing the genes necessary for their excision, conjugative transfer, and …
elements, containing the genes necessary for their excision, conjugative transfer, and …
[HTML][HTML] Chasing resistance: analyzing the fight against hospital infections
RM Wheatley, J Botelho - The Lancet Regional Health–Europe, 2023 - thelancet.com
The antibiotics we rely on to treat bacterial infections are becoming increasingly ineffective
as antibiotic resistance spreads around the globe. 1 Certain bacterial pathogens, such as …
as antibiotic resistance spreads around the globe. 1 Certain bacterial pathogens, such as …
Long-term Culturing of Pseudomonas aeruginosa in Static, Minimal Nutrient Medium Results in Increased Pyocyanin Production, Reduced Biofilm Production, and …
RE Cecil, E Ornelas, A Phan, DR Yoder-Himes - bioRxiv, 2024 - biorxiv.org
Pseudomonas aeruginosa is a multidrug-resistant opportunistic human pathogen that can
survive in many natural and anthropogenic environments. It is a leading cause of morbidity …
survive in many natural and anthropogenic environments. It is a leading cause of morbidity …
Breaking virulent: The coincidental evolution of virulence factors in bacteria.
RE Cecil - 2023 - ir.library.louisville.edu
Understanding how innocuous organisms can evolve to be pathogenic to humans is of
increasing global concern. Further, understanding how existing pathogens may evolved to …
increasing global concern. Further, understanding how existing pathogens may evolved to …