Psychedelics are serotonin 2A receptor agonists that can lead to profound changes in
perception, cognition and mood. In this review, we focus on the basic neurobiology …

Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

Psilocybin has shown promise for the treatment of mood disorders, which are often
accompanied by cognitive dysfunction including cognitive rigidity. Recent studies have …

This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Serotonergic psychedelics possess considerable therapeutic potential. Although 5-HT2A
receptor activation mediates psychedelic effects, prototypical psychedelics activate both 5 …

Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …

Psychedelics are a unique class of drug that commonly produce vivid hallucinations as well
as profound psychological and mystical experiences. A grouping of interconnected brain …

Recent breakthroughs in neurobiology indicate that the time is ripe to understand how
cellular-level mechanisms are related to conscious experience. Here, we highlight the …

Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …