A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

[HTML][HTML] Cannabidiol (CBD) as a promising anti-cancer drug

ES Seltzer, AK Watters, D MacKenzie, LM Granat… - Cancers, 2020 - mdpi.com
Recently, cannabinoids, such as cannabidiol (CBD) and Δ 9-tetrahydrocannabinol (THC),
have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Cannabidiol, neuroprotection and neuropsychiatric disorders

AC Campos, MV Fogaça, AB Sonego… - Pharmacological …, 2016 - Elsevier
Cannabidiol (CBD) is a non-psychotomimetic phytocannabinoid derived from Cannabis
sativa. It has possible therapeutic effects over a broad range of neuropsychiatric disorders …

[HTML][HTML] Review of the neurological benefits of phytocannabinoids

J Maroon, J Bost - Surgical neurology international, 2018 - ncbi.nlm.nih.gov
Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

Safety and side effects of cannabidiol, a Cannabis sativa constituent

M Machado Bergamaschi… - Current drug …, 2011 - ingentaconnect.com
Cannabidiol (CBD), a major nonpsychotropic constituent of Cannabis, has multiple
pharmacological actions, including anxiolytic, antipsychotic, antiemetic and anti …

Anticancer mechanisms of cannabinoids

G Velasco, C Sánchez, M Guzmán - Current Oncology, 2016 - mdpi.com
In addition to the well-known palliative effects of cannabinoids on some cancer-associated
symptoms, a large body of evidence shows that these molecules can decrease tumour …

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

AA Izzo, F Borrelli, R Capasso, V Di Marzo… - Trends in …, 2009 - cell.com
Δ 9-tetrahydrocannabinol binds cannabinoid (CB 1 and CB 2) receptors, which are activated
by endogenous compounds (endocannabinoids) and are involved in a wide range of …

Towards the use of cannabinoids as antitumour agents

G Velasco, C Sánchez, M Guzmán - Nature Reviews Cancer, 2012 - nature.com
Various reports have shown that cannabinoids (the active components of marijuana and
their derivatives) can reduce tumour growth and progression in animal models of cancer, in …

Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy

A Shrivastava, PM Kuzontkoski, JE Groopman… - Molecular cancer …, 2011 - AACR
Cannabidiol (CBD), a major nonpsychoactive constituent of cannabis, is considered an
antineoplastic agent on the basis of its in vitro and in vivo activity against tumor cells …