Rapid advance in oncology leads to increasing survival of oncologic patients. More and
more of them live long enough to reach either the natural age of menopause or, as a side …

Background Substantial evidence indicates that dysbiosis of the gut microbial community is
associated with colorectal neoplasia. This review aims to systematically summarise the …

Estrogen plays a protective role in colorectal cancer (CRC) and primarily functions through
estrogen receptor β (ERβ). However, clinical strategies for CRC therapy associated with …

Colorectal cancer (CRC) is the second cause of cancer-related death in both sexes
worldwide. As pre-menopausal women are less likely to develop CRC compared to age …

High intake of phytoestrogen has been reported to be associated with the prevention of
colorectal cancer (CRC). Calycosin belongs to the phytoestrogen that has been shown to …

Epidemiological studies describe estrogens as protectors in the development of colon
cancer in postmenopausal women treated with hormone replacement therapy. However, the …

Although previous studies have suggested a potential role of sex hormones in the etiology of
colorectal cancer (CRC), no study has yet examined the associations between circulating …

Background Despite intense research, the prognosis for patients with advanced colorectal
cancer (CRC) remains poor. The prostaglandin D2 receptors DP1 and DP2 are explored …

Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally,
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …

Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …