Glioblastoma Multiforme (GBM) remains the most common malignant primary brain tumor
with a dismal prognosis that rarely exceeds beyond 2 years despite extensive therapy …

Glioblastomas are the most aggressive and lethal primary astrocytic tumors of the central
nervous system. They account for 60% to 70% of all gliomas and the majority are diagnosed …

A Single-Center Experience of Dopamine Antagonist ONC201 for Recurrent Histone H3
Lysine 27-to-Methionine (H3K27M)-Mutant Glioblastoma in Adults - PMC Back to Top Skip to …

Simultaneous spatio-temporal description of tumor microvasculature, blood-brain barrier,
and immune activity is pivotal to understanding the evolution mechanisms of highly …

Background Extraneural metastasis of glioma is a rare event, often occurring in patients with
advanced disease. Genomic alterations associated with extraneural glioma metastasis …

Research into factors affecting treatment response or survival in patients with cancer
frequently involves cohorts that span the most common range of clinical outcomes, as such …

Intramedullary astrocytomas (IMAs) are rare tumors, and few studies specific to the
molecular alterations of IMAs have been performed. Recently, KIAA1549-BRAF fusions and …

Purpose Glioblastoma is a lethal brain tumor, heavily infiltrated by tumor-associated myeloid
cells (TAMCs). TAMCs are emerging as a promising therapeutic target as they suppress anti …

Background Glioblastoma (GBM) is the most common primary malignant brain tumor in
adulthood. Despite multimodality treatments, including maximal safe resection followed by …

Background Giant cell glioblastoma (gcGBM) is a rare morphological variant of IDH-wildtype
(IDHwt) GBM that occurs in young adults and have a slightly better prognosis than “classic” …