Biological applications of functionalized calixarenes

SB Nimse, T Kim - Chemical Society Reviews, 2013 - pubs.rsc.org
The functionalized calixarene derivatives exhibit remarkable properties towards organic and
bioorganic molecules. However, the ability of calixarene derivatives to form stable …

Galectin-1: a small protein with major functions

I Camby, M Le Mercier, F Lefranc, R Kiss - Glycobiology, 2006 - academic.oup.com
Galectins are a family of carbohydrate-binding proteins with an affinity for β-galactosides.
Galectin-1 (Gal-1) is differentially expressed by various normal and pathological tissues and …

Chemical biology of the sugar code

HJ Gabius, HC Siebert, S André… - …, 2004 - Wiley Online Library
A high‐density coding system is essential to allow cells to communicate efficiently and
swiftly through complex surface interactions. All the structural requirements for forming a …

Unraveling galectin-1 as a novel therapeutic target for cancer

L Astorgues-Xerri, ME Riveiro… - Cancer treatment …, 2014 - Elsevier
Galectins belong to a family of carbohydrate-binding proteins with an affinity for β-
galactosides. Galectin-1 is differentially expressed by various normal and pathologic tissues …

[PDF][PDF] Galectin-3 as a multifunctional protein

A Krześlak, A Lipińska - Cell Mol Biol Lett, 2004 - Citeseer
Galectin-3 is a 31 kDa member of a growing family of β-galactosidebinding animal lectins.
This protein is expressed in a variety of tissues and cell types and is mainly found in the …

Carbohydrate recognition by boronolectins, small molecules, and lectins

S Jin, Y Cheng, S Reid, M Li… - Medicinal research …, 2010 - Wiley Online Library
Carbohydrates are known to mediate a large number of biological and pathological events.
Small and macromolecules capable of carbohydrate recognition have great potentials as …

Growth-regulatory human galectin-1: crystallographic characterisation of the structural changes induced by single-site mutations and their impact on the …

MF López-Lucendo, D Solís, S André… - Journal of molecular …, 2004 - Elsevier
Human galectin-1 is a potent multifunctional effector that participates in specific protein–
carbohydrate and protein–protein (lipid) interactions. By determining its X-ray structure, we …

Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells

D Delacour, V Gouyer, JP Zanetta, H Drobecq… - The Journal of cell …, 2005 - rupress.org
We have previously reported that 1-benzyl-2-acetamido-2-deoxy-α-d-galactopyranoside
(GalNAcα-O-bn), an inhibitor of glycosylation, perturbed apical biosynthetic trafficking in …

Human galectin-2: novel inducer of T cell apoptosis with distinct profile of caspase activation

A Sturm, M Lensch, S André, H Kaltner… - The Journal of …, 2004 - journals.aai.org
Galectin-2 is structurally closely related to galectin-1, but has a distinct expression profile
primarily confined to the gastrointestinal tract. Prominent differences in the proximal …

Galectin-4 in normal tissues and cancer

ME Huflejt, H Leffler - Glycoconjugate journal, 2003 - Springer
Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition
domains within the same peptide chain. The two domains have all the conserved galectin …