Aging is a complex process that features a functional decline in many organelles. Although
mitochondrial dysfunction is suggested as one of the determining factors of aging, the role of …

Reactive oxygen species (ROS) have been described to induce a broad range of redox-
dependent signaling reactions in physiological conditions. Nevertheless, an excessive …

Parkinson's disease (PD) is a common age-related neurodegenerative disorder whose
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …

Intermittent short-term fasting (ISTF) and ketogenic diets (KDs) exert overlapping but not
identical effects on cell metabolism, function, and resilience. Whereas health benefits of KD …

Background There is increasing interest in therapeutic ketosis as a potential therapy for
neurodegenerative disorders–in particular, mild cognitive impairment (MCI), Alzheimer's …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder predominantly
affecting the elderly. While conventional pharmacological therapies remain the primary …

In severe cases, Parkinson's disease causes uncontrolled movements known as motor
symptoms such as dystonia, rigidity, bradykinesia, and tremors. Parkinson's disease also …

Introduction Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and Huntington's disease, are heavy burdens to global health …

Parkinson's disease (PD) is a movement disorder characterized by the progressive
degeneration of dopaminergic neurons resulting in dopamine deficiency in the striatum …

Diet and circadian rhythms have been found to have a profound impact on health, disease,
and aging. Skipping breakfast, eating late, and overeating have adverse effects on the …