Combinatorial strategies for the induction of immunogenic cell death
L Bezu, LC Gomes-da-Silva, H Dewitte… - Frontiers in …, 2015 - frontiersin.org
The term “immunogenic cell death”(ICD) is commonly employed to indicate a peculiar
instance of regulated cell death (RCD) that engages the adaptive arm of the immune system …
instance of regulated cell death (RCD) that engages the adaptive arm of the immune system …
Functions of autophagy in the tumor microenvironment and cancer metastasis
EE Mowers, MN Sharifi, KF Macleod - The FEBS journal, 2018 - Wiley Online Library
Macro‐autophagy is an ancient and highly conserved self‐degradative process that plays a
homeostatic role in normal cells by eliminating organelles, pathogens, and protein …
homeostatic role in normal cells by eliminating organelles, pathogens, and protein …
Dedicated SNARE s and specialized TRIM cargo receptors mediate secretory autophagy
Autophagy is a process delivering cytoplasmic components to lysosomes for degradation.
Autophagy may, however, play a role in unconventional secretion of leaderless cytosolic …
Autophagy may, however, play a role in unconventional secretion of leaderless cytosolic …
The Crohn's disease risk factor IRGM limits NLRP3 inflammasome activation by impeding its assembly and by mediating its selective autophagy
Several large-scale genome-wide association studies genetically linked IRGM to Crohn's
disease and other inflammatory disorders in which the IRGM appears to have a protective …
disease and other inflammatory disorders in which the IRGM appears to have a protective …
Autophagy and viral infection
Autophagy is an intracellular recycling process that maintains cellular homeostasis by
orchestrating immunity upon viral infection. Following viral infection, autophagy is often …
orchestrating immunity upon viral infection. Following viral infection, autophagy is often …
AMPK: a key regulator of energy stress and calcium-induced autophagy
R Saikia, J Joseph - Journal of Molecular Medicine, 2021 - Springer
Autophagy is a well-known cell-survival strategy orchestrated by a conserved set of proteins.
It equips the cells with mechanisms to attain homeostasis during unfavorable conditions …
It equips the cells with mechanisms to attain homeostasis during unfavorable conditions …
Research progress of microneedles in the treatment of melanoma
X Li, Z Zhao, M Zhang, G Ling, P Zhang - Journal of controlled release, 2022 - Elsevier
Melanoma is an aggressive malignancy deriving from melanocytes, which is characterized
by high tendency of metastases and mortality rate. Current therapies for melanoma, like …
by high tendency of metastases and mortality rate. Current therapies for melanoma, like …
On‐demand autophagy cascade amplification nanoparticles precisely enhanced oxaliplatin‐induced cancer immunotherapy
X Wang, M Li, K Ren, C Xia, J Li, Q Yu, Y Qiu… - Advanced …, 2020 - Wiley Online Library
Chemoimmunotherapy‐induced antitumor immune response is highly dependent on tumor
autophagy. When tumor cells are treated with chemoimmunotherapy, timely overactivated …
autophagy. When tumor cells are treated with chemoimmunotherapy, timely overactivated …
Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development
CR Figueiredo, H Kalirai, JJ Sacco… - The Journal of …, 2020 - Wiley Online Library
Immunotherapy using immune checkpoint inhibitors (ICIs) induces durable responses in
many metastatic cancers. Metastatic uveal melanoma (mUM), typically occurring in the liver …
many metastatic cancers. Metastatic uveal melanoma (mUM), typically occurring in the liver …
Autophagy and kidney inflammation
T Kimura, Y Isaka, T Yoshimori - Autophagy, 2017 - Taylor & Francis
Inflammation plays a pivotal role in pathophysiological processes of kidney diseases.
Macroautophagy/autophagy plays multiple roles in inflammatory responses, and the …
Macroautophagy/autophagy plays multiple roles in inflammatory responses, and the …