[HTML][HTML] Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning
DJ Drucker - Cell metabolism, 2021 - cell.com
The increased prevalence of obesity, diabetes, and cardiovascular risk factors in people
hospitalized with severe COVID-19 illness has engendered considerable interest in the …
hospitalized with severe COVID-19 illness has engendered considerable interest in the …
Improved COVID‐19 outcomes following statin therapy: an updated systematic review and meta‐analysis
A Vahedian-Azimi, SM Mohammadi… - BioMed research …, 2021 - Wiley Online Library
Background. Although vaccine rollout for COVID‐19 has been effective in some countries,
there is still an urgent need to reduce disease transmission and severity. We recently carried …
there is still an urgent need to reduce disease transmission and severity. We recently carried …
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression
R Hashimoto, J Takahashi, K Shirakura, R Funatsu… - Science …, 2022 - science.org
In the initial process of coronavirus disease 2019 (COVID-19), severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infects respiratory epithelial cells and then transfers …
syndrome coronavirus 2 (SARS-CoV-2) infects respiratory epithelial cells and then transfers …
Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study
Background: Lipid metabolism plays an important role in viral infections. We aimed to
assess the causal effect of lipid-lowering drugs (HMGCR inhibitiors, PCSK9 inhibitiors, and …
assess the causal effect of lipid-lowering drugs (HMGCR inhibitiors, PCSK9 inhibitiors, and …
Intermediate versus standard-dose prophylactic anticoagulation and statin therapy versus placebo in critically-ill patients with COVID-19: Rationale and design of the …
Background Microvascular and macrovascular thrombotic events are among the hallmarks
of coronavirus disease 2019 (COVID-19). Furthermore, the exuberant immune response is …
of coronavirus disease 2019 (COVID-19). Furthermore, the exuberant immune response is …
[HTML][HTML] Improved COVID-19 ICU admission and mortality outcomes following treatment with statins: a systematic review and meta-analysis
A Vahedian-Azimi, SM Mohammadi… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Results The final selected studies (n= 24 studies; 32,715 patients) showed significant
reductions in ICU admission (OR= 0.78, 95% CI: 0.58–1.06; n= 10; I 2= 58.5%) and death …
reductions in ICU admission (OR= 0.78, 95% CI: 0.58–1.06; n= 10; I 2= 58.5%) and death …
[HTML][HTML] Statins reduce mortality in patients with COVID-19: an updated meta-analysis of 147 824 patients
C Diaz-Arocutipa, B Melgar-Talavera… - International Journal of …, 2021 - Elsevier
Objectives There is conflicting evidence about the efficacy of statin use in regard to clinical
outcomes in patients with coronavirus disease 2019 (COVID-19). A systematic review and …
outcomes in patients with coronavirus disease 2019 (COVID-19). A systematic review and …
[HTML][HTML] A meta-analysis on the risk factors adjusted association between cardiovascular disease and COVID-19 severity
J Xu, W Xiao, X Liang, L Shi, P Zhang, Y Wang… - BMC public health, 2021 - Springer
Background Cardiovascular disease (CVD), one of the most common comorbidities of
coronavirus disease 2019 (COVID-19), has been suspected to be associated with adverse …
coronavirus disease 2019 (COVID-19), has been suspected to be associated with adverse …
Investigating Lipid-Modulating Agents for Prevention or Treatment of COVID-19: JACC State-of-the-Art Review
AH Talasaz, P Sadeghipour… - Journal of the American …, 2021 - jacc.org
Abstract Coronavirus disease-2019 (COVID-19) is associated with systemic inflammation,
endothelial activation, and multiorgan manifestations. Lipid-modulating agents may be …
endothelial activation, and multiorgan manifestations. Lipid-modulating agents may be …
Viral myocarditis: 1917–2020: From the Influenza A to the COVID-19 pandemics
SH Rezkalla, RA Kloner - Trends in cardiovascular medicine, 2021 - Elsevier
Myocarditis is common during viral infection with cases described as early as the influenza
pandemic of 1917, and the current COVID-19 pandemic is no exception. The hallmark is …
pandemic of 1917, and the current COVID-19 pandemic is no exception. The hallmark is …