Neuroimmune axes of the blood–brain barriers and blood–brain interfaces: bases for physiological regulation, disease states, and pharmacological interventions

MA Erickson, WA Banks - Pharmacological reviews, 2018 - ASPET
Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …

[HTML][HTML] Thyroid hormones interaction with immune response, inflammation and non-thyroidal illness syndrome

R De Luca, PJ Davis, HY Lin, F Gionfra… - Frontiers in cell and …, 2021 - frontiersin.org
The interdependence between thyroid hormones (THs), namely, thyroxine and
triiodothyronine, and immune system is nowadays well-recognized, although not yet fully …

Euthyroid sick syndrome in patients with COVID-19

R Zou, C Wu, S Zhang, G Wang, Q Zhang… - Frontiers in …, 2020 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) has been shown to affect almost every
organ throughout the body. However, it is not clear whether the thyroid gland is impaired in …

Thyroid disease in the time of COVID-19

D Dworakowska, AB Grossman - Endocrine, 2020 - Springer
The novel coronavirus disease COVID-19 is produced by SARS-CoV-2. WHO has declared
COVID-19 as a public health emergency, with the most susceptible populations (requiring …

Acute inflammation and metabolism

ML Varela, M Mogildea, I Moreno, A Lopes - Inflammation, 2018 - Springer
Inflammation is an adaptive process to the noxious stimuli that the human body is constantly
exposed to. From the local inflammatory response to a full-blown systemic inflammation, a …

Thyroid dysfunction in COVID-19 patients

R Baldelli, E Nicastri, N Petrosillo, L Marchioni… - Journal of …, 2021 - Springer
Purpose “Non thyroidal illness syndrome”(NTIS) or “euthyroid sick syndrome”(ESS) is a
possible biochemical finding in euthyroid patients with severe diseases. It is characterized …

Thyroid function analysis in COVID-19: A retrospective study from a single center

J Malik, A Malik, M Javaid, T Zahid, U Ishaq, M Shoaib - Plos one, 2021 - journals.plos.org
Background and objective Coronavirus disease 2019 (COVID-19) is an on-going epidemic
with a multitude of long-ranging effects on the physiological balance of the human body. It …

The role of thyroid hormones in heart failure

C Vale, JS Neves, M von Hafe… - … drugs and therapy, 2019 - Springer
Cardiovascular diseases are the leading cause of death worldwide. Heart failure is the
terminal manifestation of cardiovascular diseases, and its morbidity and mortality remain …

FT3/FT4 ratio is correlated with all-cause mortality, cardiovascular mortality, and cardiovascular disease risk: NHANES 2007-2012

X Lang, Y Li, D Zhang, Y Zhang, N Wu… - Frontiers in …, 2022 - frontiersin.org
Background Thyroid hormones play a vital role in maintaining the homeostasis of the
cardiovascular system. The FT3/FT4 ratio can be used to evaluate the rate of T4-to-T3 …

Mechanisms of central hypogonadism

TM Barber, I Kyrou, G Kaltsas, AB Grossman… - International Journal of …, 2021 - mdpi.com
Reproductive function depends upon an operational hypothalamo–pituitary–gonadal (HPG)
axis. Due to its role in determining survival versus reproductive strategies, the HPG axis is …