Cuproptosis-associated lncRNA establishes new prognostic profile and predicts immunotherapy response in clear cell renal cell carcinoma
S Xu, D Liu, T Chang, X Wen, S Ma, G Sun… - Frontiers in …, 2022 - frontiersin.org
Background: Clear cell renal cell carcinoma (ccRCC) accounts for 80% of all kidney cancers
and has a poor prognosis. Recent studies have shown that copper-dependent, regulated …
and has a poor prognosis. Recent studies have shown that copper-dependent, regulated …
Long noncoding RNAs in acute myeloid leukemia: functional characterization and clinical relevance
M Gourvest, P Brousset, M Bousquet - Cancers, 2019 - mdpi.com
Acute Myeloid Leukemia (AML) is the most common form of leukemia in adults with an
incidence of 4.3 per 100,000 cases per year. Historically, the identification of genetic …
incidence of 4.3 per 100,000 cases per year. Historically, the identification of genetic …
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability
N Zhang, Y Shen, H Li, Y Chen, P Zhang… - … & molecular medicine, 2022 - nature.com
Abstract N6-methyladenosine (m6A) is the most abundant posttranscriptional modification of
mRNA in eukaryotes. Recent evidence suggests that dysregulated m6A-associated proteins …
mRNA in eukaryotes. Recent evidence suggests that dysregulated m6A-associated proteins …
Investigation of potential molecular biomarkers for diagnosis and prognosis of AFP-negative HCC
Z Liu, Y Pu, Y Bao, S He - International Journal of General Medicine, 2021 - Taylor & Francis
Background Alpha-fetoprotein (AFP) is the most important diagnostic and prognostic index
of hepatocellular carcinoma (HCC). AFP-positive HCC can be easily diagnosed based on …
of hepatocellular carcinoma (HCC). AFP-positive HCC can be easily diagnosed based on …
Bifidobacterium infantis-Mediated Herpes Simplex Virus-TK/Ganciclovir Treatment Inhibits Cancer Metastasis in Mouse Model
C Wang, Y Shen, Y Ma - International Journal of Molecular Sciences, 2023 - mdpi.com
Previous studies have found that Bifidobacterium infantis-mediated herpes simplex virus-
TK/ganciclovir (BF-TK/GCV) reduces the expression of VEGF and CD146, implying tumor …
TK/ganciclovir (BF-TK/GCV) reduces the expression of VEGF and CD146, implying tumor …
Dysregulation of LINC00470 and METTL3 promotes chemoresistance and suppresses autophagy of chronic myelocytic leukaemia cells
X Lai, J Wei, X Gu, X Yao, D Zhang… - Journal of cellular and …, 2021 - Wiley Online Library
Cytoplasmic lncRNAs have been found to directly interact with target mRNAs and regulate
their stability. In this study, we aimed to study the molecular mechanism underlying the …
their stability. In this study, we aimed to study the molecular mechanism underlying the …
[HTML][HTML] miR-328-3p overexpression attenuates the malignant proliferation and invasion of liver cancer via targeting Endoplasmic Reticulum Metallo Protease 1 to …
H Lu, J Hu, J Li, W Lu, X Deng… - Annals of translational …, 2020 - ncbi.nlm.nih.gov
Background Liver cancer is one of the most common cancers worldwide. microRNAs
(miRNAs) have been recognized as minimally invasive prognostic markers for distinct types …
(miRNAs) have been recognized as minimally invasive prognostic markers for distinct types …
LINC00649 underexpression is an adverse prognostic marker in acute myeloid leukemia
C Guo, Y Gao, Q Ju, C Zhang, M Gong, Z Li - BMC cancer, 2020 - Springer
Abstract Background Long noncoding RNAs (lncRNA) play a role in leukemogenesis,
maintenance, development, and therapeutic resistance of AML. While few studies have …
maintenance, development, and therapeutic resistance of AML. While few studies have …
Tumor microenvironmental competitive endogenous RNA network and immune cells act as robust prognostic predictor of acute myeloid leukemia
Y Cheng, X Wang, P Qi, C Liu, S Wang, Q Wan… - Frontiers in …, 2021 - frontiersin.org
Acute myeloid leukemia (AML) is malignant hematologic tumors with frequent recurrence
and cause high mortality. Its fate is determined by abnormal intracellular competitive …
and cause high mortality. Its fate is determined by abnormal intracellular competitive …
Clusterization in acute myeloid leukemia based on prognostic alternative splicing signature to reveal the clinical characteristics in the bone marrow microenvironment
N Zhang, P Zhang, Y Chen, S Lou, H Zeng, J Deng - Cell & bioscience, 2020 - Springer
Background Alternative splicing (AS), a crucial post-transcriptional regulatory mechanism in
expanding the coding capacities of genomes and increasing the diversity of proteins, still …
expanding the coding capacities of genomes and increasing the diversity of proteins, still …