Imaging lung perfusion

SR Hopkins, MO Wielpütz… - Journal of Applied …, 2012 - journals.physiology.org
From the first measurements of the distribution of pulmonary blood flow using radioactive
tracers by West and colleagues (J Clin Invest 40: 1–12, 1961) allowing gravitational …

Pediatric lung MRI: currently available and emerging techniques

SD Serai, JB Rapp, LJ States… - American Journal of …, 2021 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this article is to review currently available and emerging
techniques for pediatric lung MRI for general radiologists. CONCLUSION. MRI is a radiation …

The gravitational distribution of ventilation-perfusion ratio is more uniform in prone than supine posture in the normal human lung

AC Henderson, RC Sá, RJ Theilmann… - Journal of applied …, 2013 - journals.physiology.org
The gravitational gradient of intrapleural pressure is suggested to be less in prone posture
than supine. Thus the gravitational distribution of ventilation is expected to be more uniform …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

MR imaging of the airways

J Biederer - The British Journal of Radiology, 2023 - academic.oup.com
The need for airway imaging is defined by the limited sensitivity of common clinical tests like
spirometry, lung diffusion (DLCO) and blood gas analysis to early changes of peripheral …

Advances in functional and structural imaging of the human lung using proton MRI

GW Miller, JP Mugler III, RC Sá, TA Altes… - NMR in …, 2014 - Wiley Online Library
The field of proton lung MRI is advancing on a variety of fronts. In the realm of functional
imaging, it is now possible to use arterial spin labeling (ASL) and oxygen‐enhanced …

Lung-targeted delivery of cepharanthine by an erythrocyte-anchoring strategy for the treatment of acute lung injury

J Zheng, C Lu, M Yang, J Sun, J Zhang, Y Meng… - Pharmaceutics, 2022 - mdpi.com
As one of the most frequent complications of critical illness, acute lung injury (ALI) carries a
high risk of clinical morbidity and mortality. Cepharanthine (CPA) has significant anti …

3D MRI of impaired hyperpolarized 129Xe uptake in a rat model of pulmonary fibrosis

ZI Cleveland, RS Virgincar, Y Qi… - NMR in …, 2014 - Wiley Online Library
A variety of pulmonary pathologies, in particular interstitial lung diseases, are characterized
by thickening of the pulmonary blood–gas barrier, and this thickening results in reduced gas …

[HTML][HTML] Ventilation/perfusion relationships and gas exchange: measurement approaches

SR Hopkins - Comprehensive Physiology, 2020 - ncbi.nlm.nih.gov
Abstract Ventilation-perfusion (VA/Q) matching, the regional matching of the flow of fresh gas
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …

Variable lung density consideration in attenuation correction of whole-body PET/MRI

HR Marshall, FS Prato, L Deans… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Present attenuation-correction algorithms in whole-body PET/MRI do not consider variations
in lung density, either within or between patients; this may adversely affect accurate …