Preliminary Toxicity Evaluation of a Porphyrin Photosensitizer in an Alternative Preclinical Model

MC Malacarne, M Mastore, MB Gariboldi… - International Journal of …, 2023 - mdpi.com
In photodynamic therapy (PDT), a photosensitizer (PS) excited with a specific wavelength,
and in the presence of oxygen, gives rise to photochemical reactions that lead to cell …

Safety attributes of Pseudomonas sp. P26, an environmental microorganism with potential application in contaminated environments

CB Lobo, RDI Molina, PM Mochi, JM Vargas… - Environmental …, 2024 - Elsevier
Currently, the selection of non-pathogenic microorganisms that lack clinically relevant
antimicrobial resistance is crucial to bioaugmentation strategies. Pseudomonas sp. P26 …

Ergot Alkaloids Contribute to the Pathogenic Potential of the Fungus Aspergillus leporis

AM Jones, DG Panaccione - Applied and Environmental …, 2023 - Am Soc Microbiol
Opportunistically pathogenic fungi have varying potential to cause disease in animals.
Factors contributing to their virulence include specialized metabolites, which in some cases …

Temperatures above 37°C increase virulence of a convergent Klebsiella pneumoniae sequence type 307 strain

JU Müller, M Schwabe, LS Swiatek… - Frontiers in Cellular …, 2024 - frontiersin.org
Background Convergence of Klebsiella pneumoniae (KP) pathotypes has been increasingly
reported in recent years. These pathogens combine features of both multidrug-resistant and …

Identification of small RNAs associated with RNA chaperone Hfq reveals a new stress response regulator in Actinobacillus pleuropneumoniae

GC da Silva, CC Rossi, JN Rosa, NM Sanches… - Frontiers in …, 2022 - frontiersin.org
The RNA chaperone Hfq promotes the association of small RNAs (sRNAs) with cognate
mRNAs, controlling the expression of bacterial phenotype. Actinobacillus …

Klebsiella pneumoniae DedA family proteins have redundant roles in divalent cation homeostasis and resistance to phagocytosis

V Tiwari, A Sharma, R Braga, E Garcia… - Microbiology …, 2024 - Am Soc Microbiol
The DedA superfamily is a highly conserved family of membrane proteins. Deletion of
Escherichia coli yqjA and yghB, encoding related DedA family proteins, results in sensitivity …

Exploring the potential of root-associated bacteria to control an outbreak weed

X Liu, K Vrieling, SIF Gomes, A Ossowicki… - Plant and Soil, 2024 - Springer
Aims The spread of invasive weeds threatens biodiversity and stability of ecosystems.
Jacobaea vulgaris is an invasive weed in some countries and an outbreak species in its …

An ELISA-based method for Galleria mellonella apolipophorin-III quantification

U Ramírez-Sotelo, LC García-Carnero… - PeerJ, 2024 - peerj.com
Mammalian models, such as murine, are used widely in pathophysiological studies because
they have a high degree of similarity in body temperature, metabolism, and immune …

Galleria mellonella Invertebrate Model Mirrors the Pathogenic Potential of Mycoplasma alligatoris within the Natural Host

AM Burne, LJ Richey, TR Schoeb… - Transboundary and …, 2024 - Wiley Online Library
Most mycoplasmal infections result in chronic, clinically silent disease. In direct contrast,
Mycoplasma alligatoris elicits a fulminant, multisystem disease in the natural host, Alligator …

Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature

I Rodrigues Lopes, LM Alcantara, RJ Silva… - Nature …, 2022 - nature.com
Staphylococcus aureus is increasingly recognized as a facultative intracellular pathogen,
although the significance and pervasiveness of its intracellular lifestyle remain controversial …