Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo
M Benvenuto, V Angiolini, C Focaccetti, D Nardozi… - Biology Direct, 2023 - Springer
Background Malignant mesothelioma (MM) is a rare tumor with a dismal prognosis. The low
efficacy of current treatment options highlights the urge to identify more effective therapies …
efficacy of current treatment options highlights the urge to identify more effective therapies …
A highly selective and sensitive endoplasmic reticulum-targeted probe reveals HOCl-and cisplatin-induced H 2 S biogenesis in live cells
H Ye, S Liu, Z Chen, L Cheng, L Yi - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Reactive oxygen species (ROS) and reactive sulfur species (RSS) are involved in many
physiological processes and act as collaborators with crosstalk. As an important member of …
physiological processes and act as collaborators with crosstalk. As an important member of …
Targeting the ribosome to treat multiple myeloma
The high rates of protein synthesis and processing render multiple myeloma (MM) cells
vulnerable to perturbations in protein homeostasis. The induction of proteotoxic stress by …
vulnerable to perturbations in protein homeostasis. The induction of proteotoxic stress by …
Single-cell transcriptomic atlas throughout anti-BCMA CAR-T therapy in patients with multiple myeloma
Y Xia, Q Zhao, X Shen, Y Jin, J Wang, J Zhu… - Frontiers in …, 2023 - frontiersin.org
Introduction The emergence of chimeric antigen receptor (CAR)-T therapy targeting B cell
maturation antigen (BCMA) has improved the prognosis of patients with multiple myeloma …
maturation antigen (BCMA) has improved the prognosis of patients with multiple myeloma …
Integrative analysis of an endoplasmic reticulum stress‐related signature in multiple myeloma
C Wu, M Liu, J Liu, M Jia, X Zeng, Z Fu… - The Journal of Gene …, 2024 - Wiley Online Library
Background Multiple myeloma (MM) is a malignancy in which plasma cells proliferate
abnormally, and it remains incurable. The cells are characterized by high levels of …
abnormally, and it remains incurable. The cells are characterized by high levels of …
[HTML][HTML] Liposomes have a direct effect on multiple myeloma: a Mendelian randomization study
Y Zhong, Y Li, W Sun, M Xiao - Frontiers in Oncology, 2024 - ncbi.nlm.nih.gov
Background Multiple myeloma (MM), a malignant disease of plasma cells originating in the
bone marrow, is influenced significantly by genetic factors. Although plasma liposomes have …
bone marrow, is influenced significantly by genetic factors. Although plasma liposomes have …
Role of BACH1 in multiple myeloma
Y Chen, Z Zeng, J Chen - Hematology, 2024 - Taylor & Francis
ABSTRACT Objective Examine Bach1 protein expression in bone marrow biopsy specimens
obtained from newly diagnosed multiple myeloma (NDMM) and iron deficiency anemia (IDA) …
obtained from newly diagnosed multiple myeloma (NDMM) and iron deficiency anemia (IDA) …
Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling
Understanding the spatial organization of the bone marrow (BM) microenvironment at single-
cell resolution constitutes a challenge in multiple myeloma (MM). Using formalin-fixed …
cell resolution constitutes a challenge in multiple myeloma (MM). Using formalin-fixed …
Targeting the ribosome to treat multiple myeloma
The high rates of protein synthesis and processing render multiple myeloma (MM) cells
vulnerable to perturbations in protein homeostasis. The induction of proteotoxic stress by …
vulnerable to perturbations in protein homeostasis. The induction of proteotoxic stress by …
Research progress on the beneficial effects of exercise on endocrine system-related diseases in women by regulating ER stress pathways
D Chen, S Zhang, S Sheng, L Cai, J Zheng, Y Zhang… - 2023 - researchsquare.com
Exercise, as an effective non-drug intervention, plays an important role in preventing and
alleviating several diseases. Endoplasmic reticulum (ER) stress is caused by an excessive …
alleviating several diseases. Endoplasmic reticulum (ER) stress is caused by an excessive …