Emerging role of ferroptosis in diabetic retinopathy: a review
R Wang, S Rao, Z Zhong, K Xiao, X Chen… - Journal of Drug …, 2024 - Taylor & Francis
Background Diabetic retinopathy (DR) is a significant complication of diabetes and the
primary cause of blindness among working age adults globally. The development of DR is …
primary cause of blindness among working age adults globally. The development of DR is …
Understanding the Impact of Polyunsaturated Fatty Acids on Age-Related Macular Degeneration: A Review
M Brito, C Sorbier, N Mignet, V Boudy… - International Journal of …, 2024 - mdpi.com
Age-related Macular Degeneration (AMD) is a multifactorial ocular pathology that destroys
the photoreceptors of the macula. Two forms are distinguished, dry and wet AMD, with …
the photoreceptors of the macula. Two forms are distinguished, dry and wet AMD, with …
Piceid octanoate protects retinal cells against oxidative damage by regulating the Sirtuin 1/poly-ADP-ribose polymerase 1 Axis In Vitro and in rd10 Mice
SM Moshtaghion, E Caballano-Infantes, Á Plaza Reyes… - Antioxidants, 2024 - mdpi.com
Retinitis pigmentosa is a common cause of inherited blindness in adults, which in many
cases is associated with an increase in the formation of reactive oxygen species (ROS) that …
cases is associated with an increase in the formation of reactive oxygen species (ROS) that …
Mendelian Randomization Analysis Reveals Causal Effects of Polyunsaturated Fatty Acids on Subtypes of Diabetic Retinopathy Risk
S Ren, C Xue, M Xu, X Li - Nutrients, 2023 - mdpi.com
Polyunsaturated fatty acids (PUFAs) affect several physiological processes, including visual
acuity, but their relationship with diabetic retinopathy (DR) remains elusive. The aim of this …
acuity, but their relationship with diabetic retinopathy (DR) remains elusive. The aim of this …
Uncovering the role of ferroptosis in Bietti crystalline dystrophy and potential therapeutic strategies
C Shen, Q Yang, K Chen, H Ma, X Wang… - Cell Communication and …, 2024 - Springer
Purpose Bietti crystalline dystrophy (BCD) is an inherited retinal degeneration disease
caused by mutations in the CYP4V2 gene. Currently, there is no clinical therapy approach …
caused by mutations in the CYP4V2 gene. Currently, there is no clinical therapy approach …
Docosahexaenoic Acid Coordinating with Sodium Selenite Promotes Paraptosis in Colorectal Cancer Cells by Disrupting the Redox Homeostasis and Activating the …
S Zhao, Y Meng, W Cai, Q Luo, H Gao, Q Shen, D Shi - Nutrients, 2024 - mdpi.com
Tumor cells are characterized by a delicate balance between elevated oxidative stress and
enhanced antioxidant capacity. This intricate equilibrium, maintained within a threshold …
enhanced antioxidant capacity. This intricate equilibrium, maintained within a threshold …
Generating Bone Marrow Chimeric Mouse Using GPR120 Deficient Mouse for the Study of DHA Inhibitory Effect on Osteoclast Formation and Bone Resorption
J Ma, H Kitaura, F Ohori, T Noguchi… - International Journal of …, 2023 - mdpi.com
Docosahexaenoic acid (DHA) is an omega-3 fatty acid that exerts physiological effects via G
protein-coupled receptor 120 (GPR120). In our previous studies, we figured out the …
protein-coupled receptor 120 (GPR120). In our previous studies, we figured out the …
Role of plasma fatty acid in age-related macular degeneration: insights from a mendelian randomization analysis
G Han, P Wei, M He, L Jia, Q Su, X Yang… - Lipids in Health and …, 2024 - Springer
Background An imbalance in lipid metabolism has been linked to the development of AMD,
but the causal relationship between AMD and plasma fatty acids (FAs) remains …
but the causal relationship between AMD and plasma fatty acids (FAs) remains …
DHA shortage causes the early degeneration of photoreceptors and RPE in mice with peroxisomal β-oxidation deficiency
D Swinkels, S Kocherlakota, Y Das… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: Patients deficient in peroxisomal β-oxidation, which is essential for the synthesis of
docosahexaenoic acid (DHA, C22: 6n-3) and breakdown of very-long-chain polyunsaturated …
docosahexaenoic acid (DHA, C22: 6n-3) and breakdown of very-long-chain polyunsaturated …
Fatty Acid Metabolism in Peroxisomes and Related Disorders
K Morito, H Ali, S Kishino, T Tanaka - 2024 - Springer
One of the functions of peroxisomes is the oxidation of fatty acids (FAs). The importance of
this function in our lives is evidenced by the presence of peroxisomal disorders caused by …
this function in our lives is evidenced by the presence of peroxisomal disorders caused by …