Ovarian cancer (OC) is one of the leading causes of cancer-related deaths in women. Most
patients are diagnosed with advanced epithelial OC in their late 60s, and early-onset adult …

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling
pathway serves as a pivotal mediator of innate immunity by triggering the secretion of type I …

Whales are marine creatures known for their enormous size and that live in all the oceans
on earth. One of the oldest known organisms is bowhead whales, which can survive up to …

Hereditary cancer syndromes (HCSs) are arguably the most frequent category of Mendelian
genetic diseases, as at least 2% of presumably healthy subjects carry highly-penetrant …

The proteins encoded by the excision repair cross-complementing (ERCC) family are pivotal
in DNA damage repair and maintaining genome stability. However, the precise role of the …

Early adenocarcinoma mixed with a neuroendocrine carcinoma component arising in the
gastroesophageal junction: A case report - PMC Back to Top Skip to main content NIH NLM …

Purpose It is well known that individuals with hereditary retinoblastoma are at lifelong high
risk for developing subsequent malignant neoplasms (SMN). However, the role that non …

We have read with interest the article by Stradella et al.[1], suggesting ERCC3 as a new
gene predisposing the hereditary breast (BC) and ovarian (OC) cancer. The authors …

Multiple oncological societies' guidelines recommend for patients with variants detected on
tumor-only genomic profiling that are suspicious of being germline in origin be referred for …

We have carefully read the results presented by the CZECANCA consortium (presented by
Soukupova on behalf of the CZECANCA consortium). First of all, we would like to thank them …