Safety of Switching From a Vitamin K Antagonist to a Non–Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients With Atrial Fibrillation: Results of the FRAIL …

LPT Joosten, S van Doorn, PM van de Ven… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: There is ambiguity whether frail patients with atrial fibrillation managed with
vitamin K antagonists (VKAs) should be switched to a non–vitamin K oral anticoagulant …

Gastrointestinal bleeding due to NOACs use: exploring the molecular mechanisms

A Saviano, M Brigida, C Petruzziello… - International Journal of …, 2022 - mdpi.com
Novel oral anticoagulants (NOACs) are drugs approved for the prevention and treatment of
many thromboembolic cardiovascular conditions as a safer alternative to warfarin. We …

Gastrointestinal dysfunction in stroke

HYF Yong, A Ganesh… - Seminars in …, 2023 - thieme-connect.com
Gastrointestinal (GI) complications are seen in over 50% of ischemic stroke survivors; the
most common complications are dysphagia, constipation, and GI bleeding. The bidirectional …

[HTML][HTML] Antithrombotic treatment in patients with hemophilia: an EHA-ISTH-EAHAD-ESO clinical practice guidance

REG Schutgens, V Jimenez-Yuste, M Escobar… - …, 2023 - journals.lww.com
Cardiovascular disease is an emerging medical issue in patients with hemophilia (PWH)
and its prevalence is increasing up to 15% in PWH in the United States. Atrial fibrillation …

[PDF][PDF] Consensus document of the Spanish Society of Digestives Diseases and the Spanish Society of Thrombosis and Haemostasis on massive nonvariceal …

FC Álvarez, AA Martínez, PL Silero, AO Calzada… - Rev Esp Enferm …, 2022 - online.reed.es
Introduction: there is limited experience and understanding of massive nonvariceal
gastrointestinal bleeding during therapy with direct-acting oral anticoagulants. Objectives: to …

Differences in the location of bleeding with direct oral anticoagulants vs. vitamin K antagonists: A study in the World Health Organization's pharmacovigilance …

JL Montastruc, S Tessier… - British Journal of Clinical …, 2023 - Wiley Online Library
Aims Clinical trials have found differences in bleeding locations between direct oral
anticoagulants (DOAC) and vitamin K antagonists (VKA). The present study was performed …

[HTML][HTML] Risk factors for anticoagulant-associated gastrointestinal hemorrhage: a systematic review and meta-analysis

F Ma, S Wu, S Li, Z Zeng, J Zhang - The Korean Journal of Internal …, 2024 - ncbi.nlm.nih.gov
Methods A systematic review and meta-analysis were conducted to search PubMed,
EMBASE, Web of Science, and Cochrane Library databases (from inception through …

Safety and efficacy of direct oral anticoagulants in stroke prevention in patients with atrial fibrillation complicated with anemia and/or thrombocytopenia: a retrospective …

W Xu, J Chen, S Wu, N Huang, X Chen, W Zhang… - Thrombosis …, 2023 - Springer
Background There are limited data about the clinical benefits and harm of direct oral
anticoagulants (DOACs) in stroke prevention in patients with atrial fibrillation (AF) …

Effects of direct oral anticoagulants dabigatran and rivaroxaban on the blood coagulation function in rabbits

L Yin, Y Qi, Z Ge, J Li - Open Life Sciences, 2022 - degruyter.com
The aim of this study was to explore the effects of dabigatran and rivaroxaban on the
activities of various coagulation factors. To achieve that, 60 rabbits were randomly divided …

Documento de consenso de la Sociedad Española de Patología Digestiva y de la Sociedad Española de Trombosis y Hemostasia sobre hemorragia digestiva masiva …

F Carballo, E Redondo Cerezo - 2022 - digibug.ugr.es
Introducción: existe limitada experiencia y conocimiento sobre la hemorragia digestiva
masiva no varicosa durante el tratamiento con anticoagulantes orales de acción directa …