Purpose.: In the vertebrate retina, calcium-activated chloride channels are expressed in
photoreceptor synaptic terminals. These channels are involved in the control of transmitter …

We examined the contribution of calcium‐induced calcium release (CICR) to synaptic
transmission from rod photoreceptor terminals. Whole‐cell recording and confocal calcium …

Voltage-gated Ca2+ channels allow for Ca2+-dependent intracellular signaling by directly
mediating Ca2+ ion influx, by physical coupling to intracellular Ca2+ release channels or …

This review lays out the emerging evidence for the fundamental role of Ca 2+ stores and
store-operated channels in the Ca 2+ homeostasis of rods and cones. Calcium-induced …

Trafficking of transducin (Gαt) in rod photoreceptors is critical for adaptive and modulatory
responses of the retina to varying light intensities. In addition to fine-tuning …

Mammals can see at low scotopic light levels where only 1 rod in several thousand
transduces a photon. The single photon signal is transmitted to the brain by the ganglion …

Congenital stationary night blindess-2 (incomplete congenital stationary night blindness
(iCSNB) or CSNB-2) is a nonprogressive, X-linked retinal disease which can lead to clinical …

Changes in intracellular calcium ions [Ca2+] play important roles in photoreceptor signaling.
Consequently, intracellular [Ca2+] levels need to be tightly controlled. In the light-sensitive …

The retina can function under a variety of adaptation conditions and stimulus paradigms. To
adapt to these various conditions, modifications in the phototransduction cascade and at the …

Abstract L‐type Ca2+ currents (ICa) in rod photoreceptors exhibit Ca2+‐dependent
inactivation. Perforated‐patch whole‐cell recordings were obtained from isolated rods of the …