Molecular panorama of therapy resistance in prostate cancer: a pre-clinical and bioinformatics analysis for clinical translation
Prostate cancer (PCa) is a malignant disorder of prostate gland being asymptomatic in early
stages and high metastatic potential in advanced stages. The chemotherapy and surgical …
stages and high metastatic potential in advanced stages. The chemotherapy and surgical …
Cannabidiol and neurodegeneration: From molecular mechanisms to clinical benefits
SK Jha, VK Nelson, PR Suryadevara, SP Panda… - Ageing Research …, 2024 - Elsevier
Neurodegenerative disorders (NDs) such as Alzheimer's disease, Parkinson's disease,
Huntington's disease, multiple sclerosis, and amyotrophic lateral sclerosis are severe and …
Huntington's disease, multiple sclerosis, and amyotrophic lateral sclerosis are severe and …
[HTML][HTML] Cannabidiol attenuates inflammatory impairment of intestinal cells expanding biomaterial-based therapeutic approaches
E Boehm, L Droessler, S Amasheh - Materials Today Bio, 2023 - Elsevier
Cannabis-based biomaterials have the potential to deliver anti-inflammatory therapeutics
specifically to desired cells, tissues, and organs, enhancing drug delivery and the …
specifically to desired cells, tissues, and organs, enhancing drug delivery and the …
Cbd inhibits in vivo development of human breast cancer tumors
L García-Morales, MG Mendoza-Rodríguez… - International Journal of …, 2023 - mdpi.com
Inflammation is a critical component of cancer development. Previously, we showed in vitro
that IL-1β treatment of non-invasive human breast cancer MCF-7 cells promoted their …
that IL-1β treatment of non-invasive human breast cancer MCF-7 cells promoted their …
[HTML][HTML] Therapeutic potentials of cannabidiol: Focus on the Nrf2 signaling pathway
Cannabidiol (CBD), a cannabinoid that does not create psychoactive activities, has been
identified as having a multitude of therapeutic benefits. This study delves into the chemical …
identified as having a multitude of therapeutic benefits. This study delves into the chemical …
[HTML][HTML] Exosomal microRNAs in regulation of tumor cells resistance to apoptosis
Exosomes are a type of extracellular vesicle that contains bioactive molecules that can be
secreted by most cells. Nevertheless, the content of these cells differs depending on the cell …
secreted by most cells. Nevertheless, the content of these cells differs depending on the cell …
Ginkgolide A attenuated apoptosis via inhibition of oxidative stress in mice with traumatic brain injury
L Zhu, Z Li, L Sheng, F Zhang, W Ji - Heliyon, 2024 - cell.com
Traumatic brain injury (TBI) is the main cause of death among young adults and the main
cause of mortality and disability for all ages groups worldwide. Ginkgolides terpenoid …
cause of mortality and disability for all ages groups worldwide. Ginkgolides terpenoid …
A comprehensive update on cannabidiol, its formulations and drug delivery systems
S Banerjee, VA Saharan, D Banerjee, V Ram… - Phytochemistry …, 2024 - Springer
Cannabis sativa, the debatable plant, contains a vast array of phytocannabinoids, with a
significant presence of cannabidiol. This cannabinoid possesses numerous medicinal …
significant presence of cannabidiol. This cannabinoid possesses numerous medicinal …
Analysis of the action mechanisms and targets of herbal anticonvulsants highlights opportunities for therapeutic engagement with refractory epilepsy
Epilepsy is a neurological disorder characterized by spontaneous and recurring seizures. It
poses significant therapeutic challenges due to diverse etiology, pathobiology, and …
poses significant therapeutic challenges due to diverse etiology, pathobiology, and …
[HTML][HTML] Bioactive Properties and In Vitro Digestive Release of Cannabidiol (CBD) from Tailored Composites Based on Carbon Materials
K Zapata, AD Vélez, JA Correa, F Carrasco-Marín… - Pharmaceutics, 2024 - mdpi.com
The use of carriers to improve cannabidiol (CBD) bioavailability during digestion is at the
forefront of research. The main objective of this research was to evaluate CBD bioactivity …
forefront of research. The main objective of this research was to evaluate CBD bioactivity …