[HTML][HTML] Key chemokines direct migration of immune cells in solid tumors

K Kohli, VG Pillarisetty, TS Kim - Cancer gene therapy, 2022 - nature.com
Immune cell infiltration into solid tumors, their movement within the tumor microenvironment
(TME), and interaction with other immune cells are controlled by their directed migration …

Crosstalk between ferroptosis and the epithelial-mesenchymal transition: Implications for inflammation and cancer therapy

N Ebrahimi, S Adelian, S Shakerian… - Cytokine & growth factor …, 2022 - Elsevier
Both genomic instability and the presence of chronic inflammation are involved in
carcinogenesis and tumor progression. These alterations predispose the cancer cells to …

Diagnosis and management of Barrett's esophagus: an updated ACG guideline

NJ Shaheen, GW Falk, PG Iyer, RF Souza… - Official journal of the …, 2022 - journals.lww.com
Barrett's esophagus (BE) is a common condition associated with chronic gastroesophageal
reflux disease. BE is the only known precursor to esophageal adenocarcinoma, a highly …

Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative …

Z Memariani, SQ Abbas, SS Ul Hassan… - Pharmacological …, 2021 - Elsevier
Although the rates of many cancers are controlled in Western countries, those of some
cancers, such as lung, breast, and colorectal cancer are currently increasing in many low …

[HTML][HTML] Non-steroidal anti-inflammatory drugs: Recent advances in the use of synthetic COX-2 inhibitors

M Ahmadi, S Bekeschus, KD Weltmann… - RSC Medicinal …, 2022 - pubs.rsc.org
Cyclooxygenase (COX) enzymes comprise COX-1 and COX-2 isoforms and are responsible
for prostaglandin production. Prostaglandins have critical roles in the inflammation pathway …

[HTML][HTML] The therapeutic potential of targeting tryptophan catabolism in cancer

CA Opitz, LF Somarribas Patterson… - British journal of …, 2020 - nature.com
Based on its effects on both tumour cell intrinsic malignant properties as well as anti-tumour
immune responses, tryptophan catabolism has emerged as an important metabolic regulator …

Immune escape: A critical hallmark in solid tumors

K Mortezaee - Life sciences, 2020 - Elsevier
Incapacitated immune system is a characteristic hallmark of solid tumors. Immune system
within a tumor undergoes an imbalance in cellular dispersion and functionality. Effector cells …

[HTML][HTML] Beta-sitosterol as a promising anticancer agent for chemoprevention and chemotherapy: Mechanisms of action and future prospects

H Wang, Z Wang, Z Zhang, J Liu, L Hong - Advances in Nutrition, 2023 - Elsevier
Cancer is one of the primary causes of death worldwide and its incidence continues to
increase year by year. Despite significant advances in research, the search for effective and …

[HTML][HTML] Traditional Chinese medicine for precancerous lesions of gastric cancer: a review

W Xu, B Li, M Xu, T Yang, X Hao - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Gastric cancer (GC) is the fifth most common type of cancer and the third leading cause of
death due to cancer worldwide. The gastric mucosa often undergoes many years of …

Platinum prodrug nanoparticles with COX‐2 inhibition amplify pyroptosis for enhanced chemotherapy and immune activation of pancreatic cancer

B Yu, Y Wang, T Bing, Y Tang, J Huang… - Advanced …, 2024 - Wiley Online Library
Pyroptosis, an emerging mechanism of programmed cell death, holds great potential to
trigger a robust antitumor immune response. Platinum‐based chemotherapeutic agents can …