The role of pharmacogenomics in adverse drug reactions
R Cacabelos, N Cacabelos, JC Carril - Expert Review of Clinical …, 2019 - Taylor & Francis
ABSTRACT Introduction: Adverse drug reactions (ADRs) are a major health concern
worldwide. There are multiple causes of ADRs, some of which are preventable …
worldwide. There are multiple causes of ADRs, some of which are preventable …
[HTML][HTML] Association of CYP3A4-392A/G, CYP3A5-6986A/G, and ABCB1-3435C/T Polymorphisms with Tacrolimus Dose, Serum Concentration, and Biochemical …
EV Alatorre-Moreno, AM Saldaña-Cruz… - Genes, 2024 - mdpi.com
Tacrolimus (TAC) is an immunosuppressant drug that prevents organ rejection after
transplantation. This drug is transported from cells via P-glycoprotein (ABCB1) and is a …
transplantation. This drug is transported from cells via P-glycoprotein (ABCB1) and is a …
Influence of genetic variants and antiepileptic drug co-treatment on lamotrigine plasma concentration in Mexican Mestizo patients with epilepsy
Genetic and nongenetic factors may contribute to lamotrigine (LTG) plasma concentration
variability among patients. We simultaneously investigated the association of UGT1A1 …
variability among patients. We simultaneously investigated the association of UGT1A1 …
Correlation of CYP2D6 allelic polymorphism to outcome of acute coronary syndrome in mid-Euphrates Iraqi patients on metoprolol therapy
This study aims to investigate the different clinically relevant allele variants (allele
frequencies) of CYP2D6 gene and to determine whether a specific genotype of CYP2D6 …
frequencies) of CYP2D6 gene and to determine whether a specific genotype of CYP2D6 …
Clinical utility of ABCB1 and ABCG2 genotyping for assessing the clinical and pathological response to FAC therapy in Mexican breast cancer patients
E Turiján-Espinoza, VM Ruíz-Rodríguez… - Cancer Chemotherapy …, 2021 - Springer
Purpose Resistance to neoadjuvant chemotherapy with 5-fluorouracil, doxorubicin, and
cyclophosphamide (FAC) in some patients with locally advanced breast cancer remains one …
cyclophosphamide (FAC) in some patients with locally advanced breast cancer remains one …
[HTML][HTML] Bioinformatics in Mexico: A diagnostic from the academic perspective and recommendations for a public policy
D Armenta-Medina, C Díaz de León-Castañeda… - Plos one, 2020 - journals.plos.org
In this work, we present a diagnostic analysis of strengths, weaknesses, opportunities and
threats (SWOT) of the current state of Bioinformatics in Mexico. We conducted semi …
threats (SWOT) of the current state of Bioinformatics in Mexico. We conducted semi …
Changes in indigenous population structure in colonial Mexico City and Morelos
CS Ragsdale, C Willermet… - International Journal of …, 2019 - Wiley Online Library
The Spanish conquest and colonization of Mexico had disastrous effects on indigenous
people. Disease, coupled with drastic changes in the economic, political, and religious …
people. Disease, coupled with drastic changes in the economic, political, and religious …
Analysis of the TSER and G>C variants in the TYMS gene: a high frequency of low expression genotypes predicted in the Mexican population
AF Favela-Mendoza, AD Godínez-López… - Annals of Human …, 2023 - Taylor & Francis
Background In the TYMS gene promoter, there is a repeat polymorphism (TSER) that affects
the expression level of the thymidylate synthetase (TS) enzyme involved in the response to …
the expression level of the thymidylate synthetase (TS) enzyme involved in the response to …
Prevalence of Protective Haplotypes of the SLCO1B1 Gene for Statin Transport in Mexican Populations
AF Favela-Mendoza… - Personalized …, 2021 - Taylor & Francis
Aim: To evaluate the genetic distribution of the rs4149056 and rs2306283 variants in the
SLCO1B1 gene in Mexican Mestizo (admixed) and Native American groups. Materials & …
SLCO1B1 gene in Mexican Mestizo (admixed) and Native American groups. Materials & …
Estudio de la influencia de compuestos bioactivos/polimorfismos de un sólo nucleótido asociados a osteosarcoma en población amerindia
MU SANTANA - 2022 - riaa.uaem.mx
El osteosarcoma es la neoplasia ósea más común entre adolescentes y adultos jóvenes. Es
una enfermedad muy agresiva, en donde la superivencia a 5 años se estima alrededor del …
una enfermedad muy agresiva, en donde la superivencia a 5 años se estima alrededor del …