[HTML][HTML] Redox regulation of the immune response

G Morris, M Gevezova, V Sarafian… - Cellular & Molecular …, 2022 - nature.com
The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

[HTML][HTML] Functional role of dietary intervention to improve the outcome of COVID-19: a hypothesis of work

G Messina, R Polito, V Monda, L Cipolloni… - International journal of …, 2020 - mdpi.com
Background: On the 31 December 2019, the World Health Organization (WHO) was
informed of a cluster of cases of pneumonia of unknown origin detected in Wuhan City …

[HTML][HTML] Adaptive immunity: an emerging player in the progression of NAFLD

S Sutti, E Albano - Nature Reviews Gastroenterology & Hepatology, 2020 - nature.com
In the past decade, nonalcoholic fatty liver disease (NAFLD) has become a leading cause of
chronic liver disease and cirrhosis, as well as an important risk factor for hepatocellular …

[HTML][HTML] Complement system part I–molecular mechanisms of activation and regulation

NS Merle, SE Church, V Fremeaux-Bacchi… - Frontiers in …, 2015 - frontiersin.org
Complement is a complex innate immune surveillance system, playing a key role in defense
against pathogens and in host homeostasis. The complement system is initiated by …

Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal

A Ayala, MF Muñoz, S Argüelles - Oxidative medicine and …, 2014 - Wiley Online Library
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

[HTML][HTML] Innate sensing of oxidation-specific epitopes in health and disease

CJ Binder, N Papac-Milicevic, JL Witztum - Nature Reviews …, 2016 - nature.com
Ageing, infections and inflammation result in oxidative stress that can irreversibly damage
cellular structures. The oxidative damage of lipids in membranes or lipoproteins is one of …

Immune mechanisms linked to depression via oxidative stress and neuroprogression

N Bakunina, CM Pariante, PA Zunszain - Immunology, 2015 - Wiley Online Library
Emerging evidence suggests a significant role for inflammation and oxidative stress as main
contributors to the neuroprogression that is observed in major depressive disorder (MDD) …

B cells and humoral immunity in atherosclerosis

D Tsiantoulas, CJ Diehl, JL Witztum… - Circulation research, 2014 - Am Heart Assoc
Insights into the important contribution of inflammation and immune functions in the
development and progression of atherosclerosis have greatly improved our understanding …

[HTML][HTML] Metabolic regulation of ferroptosis in the tumor microenvironment

NE Mbah, CA Lyssiotis - Journal of Biological Chemistry, 2022 - ASBMB
Ferroptosis is an iron-dependent, nonapoptotic form of regulated cell death triggered by
impaired redox and antioxidant machinery and propagated by the accumulation of toxic lipid …

Anthracyclines/trastuzumab: new aspects of cardiotoxicity and molecular mechanisms

L Rochette, C Guenancia, A Gudjoncik… - Trends in …, 2015 - cell.com
Anticancer drugs continue to cause significant reductions in left ventricular ejection fraction
resulting in congestive heart failure. The best-known cardiotoxic agents are anthracyclines …