Upon solid organ transplantation and during cancer immunotherapy, cellular stress
responses result in the release of damage-associated molecular patterns (DAMPs). The …

Many patients with systemic immune-inflammatory and neuro-inflammatory disorders,
including depression, rheumatoid arthritis, systemic lupus erythematosus, Sjögren's disease …

Biomarkers can help unravel mechanisms of disease and identify new targets for therapy.
They can also be useful in clinical practice for monitoring disease progression, evaluation of …

Enhanced lipid peroxidation occurs during oxidative stress and results in the generation of
lipid peroxidation end products such as malondialdehyde (MDA), which can attach to …

Abstract Age-related Macular Degeneration (AMD) is the leading cause of blindness among
the elderly in western societies. While antioxidant micronutrient treatment is available for …

Significance: Oxidative stress provokes the peroxidation of polyunsaturated fatty acids in
cellular membranes, leading to the formation of aldheydes that, due to their high chemical …

The skin is exposed to environmental insults such as UV light that cause oxidative damage
to macromolecules. A centerpiece in the defense against oxidative stress is the Nrf2 (nuclear …

Deficit schizophrenia is characterized by leaky intestinal tight and adherens junctions and
bacterial translocation. Here we examine whether (deficit) schizophrenia is accompanied by …

Kawasaki disease (KD) is an acute systemic vasculitis of an unknown aetiology. A small
proportion of children exposed to severe acute respiratory syndrome coronavirus 2 (SARS …

Inadequate control of the complement system is the underlying or aggravating factor in many
human diseases. Whereas treatment options that specifically target the alternative pathway …