Potential influences of complement factor H in autoimmune inflammatory and thrombotic disorders

J Ferluga, L Kouser, V Murugaiah, RB Sim… - Molecular …, 2017 - Elsevier
Complement system homeostasis is important for host self-protection and anti-microbial
immune surveillance, and recent research indicates roles in tissue development and …

Oxolipidomics profile in major depressive disorder: Comparing remitters and non-remitters to repetitive transcranial magnetic stimulation treatment

H Stirton, BP Meek, AL Edel, Z Solati, A Surendran… - PLoS …, 2021 - journals.plos.org
Background Repetitive Transcranial Magnetic Stimulation [rTMS] is increasingly being used
to treat Major Depressive Disorder [MDD]. Given that not all patients respond to rTMS, it …

Oxidative Deamination of Serum Albumins by (-)-Epigallocatechin-3-O-Gallate: A Potential Mechanism for the Formation of Innate Antigens by Antioxidants

Y Hatasa, M Chikazawa, M Furuhashi, F Nakashima… - PLoS …, 2016 - journals.plos.org
(-)-Epigallocatechin-3-O-gallate (EGCG), the most abundant polyphenol in green tea,
mediates the oxidative modification of proteins, generating protein carbonyls. However, the …

Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury

Z Solati, AL Edel, Y Shang, KO, A Ravandi - PLoS One, 2018 - journals.plos.org
Background The aim of this study was to determine the individual oxidized
phosphatidylcholine (OxPC) molecules generated during renal ischemia/reperfusion (I/R) …

Identification of C1q as a binding protein for advanced glycation end products

M Chikazawa, T Shibata, Y Hatasa, S Hirose… - Biochemistry, 2016 - ACS Publications
Advanced glycation end products (AGEs) make up a heterogeneous group of molecules
formed from the nonenzymatic reaction of reducing sugars with the free amino groups of …

Free radical-decellularized tissue promotes enhanced antioxidant and anti-inflammatory macrophage response

ST LoPresti, B Popovic, M Kulkarni, CD Skillen… - Biomaterials, 2019 - Elsevier
Oxidative stress leads to the progression of many diseases including chronic wounds,
atherosclerosis, stroke and cancer. The modification of biomolecules with reactive nitrogen …

The inflammatory process underlying atherosclerosis

MT Montero-Vega - Critical Reviews™ in Immunology, 2012 - dl.begellhouse.com
Atherosclerosis is considered an inflammatory disease that starts and evolves in response to
cholesterol accumulation in the arterial intima of the large and medium arteries. In recent …

Gold nanoparticle-conjugated anti-oxidized low-density lipoprotein antibodies for targeted lipidomics of oxidative stress biomarkers

H Hinterwirth, G Stübiger, W Lindner… - Analytical …, 2013 - ACS Publications
Oxidized low-density lipoproteins (OxLDLs), in particular, oxidized phosphatidylcholines
(OxPCs), are known to be involved in pathophysiological processes such as cardiovascular …

Macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins are modulated by complement protein C1q

MM Ho, A Manughian-Peter, WR Spivia, A Taylor… - Atherosclerosis, 2016 - Elsevier
Background and aims This study investigated the effect of innate immune protein C1q on
macrophage programmed responses during the ingestion of atherogenic lipoproteins. C1q …

Accumulating evidence for a role of oxidized phospholipids in infectious diseases

U Matt, O Sharif, R Martins, S Knapp - Cellular and molecular life sciences, 2015 - Springer
Oxidized phospholipids (OxPL) were originally discovered as by-products and mediators of
chronic inflammation such as in atherosclerosis. Over the last years, an increasing body of …