Potential influences of complement factor H in autoimmune inflammatory and thrombotic disorders
J Ferluga, L Kouser, V Murugaiah, RB Sim… - Molecular …, 2017 - Elsevier
Complement system homeostasis is important for host self-protection and anti-microbial
immune surveillance, and recent research indicates roles in tissue development and …
immune surveillance, and recent research indicates roles in tissue development and …
Oxolipidomics profile in major depressive disorder: Comparing remitters and non-remitters to repetitive transcranial magnetic stimulation treatment
Background Repetitive Transcranial Magnetic Stimulation [rTMS] is increasingly being used
to treat Major Depressive Disorder [MDD]. Given that not all patients respond to rTMS, it …
to treat Major Depressive Disorder [MDD]. Given that not all patients respond to rTMS, it …
Oxidative Deamination of Serum Albumins by (-)-Epigallocatechin-3-O-Gallate: A Potential Mechanism for the Formation of Innate Antigens by Antioxidants
Y Hatasa, M Chikazawa, M Furuhashi, F Nakashima… - PLoS …, 2016 - journals.plos.org
(-)-Epigallocatechin-3-O-gallate (EGCG), the most abundant polyphenol in green tea,
mediates the oxidative modification of proteins, generating protein carbonyls. However, the …
mediates the oxidative modification of proteins, generating protein carbonyls. However, the …
Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury
Background The aim of this study was to determine the individual oxidized
phosphatidylcholine (OxPC) molecules generated during renal ischemia/reperfusion (I/R) …
phosphatidylcholine (OxPC) molecules generated during renal ischemia/reperfusion (I/R) …
Identification of C1q as a binding protein for advanced glycation end products
M Chikazawa, T Shibata, Y Hatasa, S Hirose… - Biochemistry, 2016 - ACS Publications
Advanced glycation end products (AGEs) make up a heterogeneous group of molecules
formed from the nonenzymatic reaction of reducing sugars with the free amino groups of …
formed from the nonenzymatic reaction of reducing sugars with the free amino groups of …
Free radical-decellularized tissue promotes enhanced antioxidant and anti-inflammatory macrophage response
Oxidative stress leads to the progression of many diseases including chronic wounds,
atherosclerosis, stroke and cancer. The modification of biomolecules with reactive nitrogen …
atherosclerosis, stroke and cancer. The modification of biomolecules with reactive nitrogen …
The inflammatory process underlying atherosclerosis
MT Montero-Vega - Critical Reviews™ in Immunology, 2012 - dl.begellhouse.com
Atherosclerosis is considered an inflammatory disease that starts and evolves in response to
cholesterol accumulation in the arterial intima of the large and medium arteries. In recent …
cholesterol accumulation in the arterial intima of the large and medium arteries. In recent …
Gold nanoparticle-conjugated anti-oxidized low-density lipoprotein antibodies for targeted lipidomics of oxidative stress biomarkers
H Hinterwirth, G Stübiger, W Lindner… - Analytical …, 2013 - ACS Publications
Oxidized low-density lipoproteins (OxLDLs), in particular, oxidized phosphatidylcholines
(OxPCs), are known to be involved in pathophysiological processes such as cardiovascular …
(OxPCs), are known to be involved in pathophysiological processes such as cardiovascular …
Macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins are modulated by complement protein C1q
MM Ho, A Manughian-Peter, WR Spivia, A Taylor… - Atherosclerosis, 2016 - Elsevier
Background and aims This study investigated the effect of innate immune protein C1q on
macrophage programmed responses during the ingestion of atherogenic lipoproteins. C1q …
macrophage programmed responses during the ingestion of atherogenic lipoproteins. C1q …
Accumulating evidence for a role of oxidized phospholipids in infectious diseases
Oxidized phospholipids (OxPL) were originally discovered as by-products and mediators of
chronic inflammation such as in atherosclerosis. Over the last years, an increasing body of …
chronic inflammation such as in atherosclerosis. Over the last years, an increasing body of …