Vascular endothelial ageing, heartbeat after heartbeat

E Thorin, N Thorin-Trescases - Cardiovascular research, 2009 - academic.oup.com
The vascular endothelium starts to age at the first heartbeat. There is no longer a need to
demonstrate that an increased resting heart rate—above 70 bpm—is associated with the …

Arterial stiffness, hypertension, and rational use of nebivolol

E Agabiti-Rosei, E Porteri, D Rizzoni - Vascular health and risk …, 2009 - Taylor & Francis
Arterial stiffness plays a key role in the pathophysiology of the cardiovascular system. Some
indices of arterial stiffness (pulse wave velocity, augmentation index, characteristics of …

Virtual and In Vitro Antiviral Screening Revive Therapeutic Drugs for COVID-19

G Bocci, SB Bradfute, C Ye, MJ Garcia… - ACS pharmacology & …, 2020 - ACS Publications
The urgent need for a cure for early phase COVID-19 infected patients critically underlines
drug repositioning strategies able to efficiently identify new and reliable treatments by …

Neuroprotective effect of nebivolol against cisplatin‐associated depressive‐like behavior in rats

NF Abdelkader, MA Saad… - Journal of …, 2017 - Wiley Online Library
One‐third of cancer patients undergoing chemotherapy treatment often display symptoms of
depression leading to poor adherence and decreased quality of life. Thus, this study aimed …

Nanosized ethosomal dispersions for enhanced transdermal delivery of nebivolol using intradermal/transfollicular sustained reservoir: in vitro evaluation, confocal laser …

SA Fouad, ST Khatab, MH Teaima… - Pharmaceutical …, 2024 - Taylor & Francis
Nebivolol (NBV), a BCS class II anti-hypertensive drug, suffers from limited solubility and
oral bioavailability. Nanosized ethosomes were adopted as an approach to solubilize and …

Effect of beta-1-blocker, nebivolol, on central aortic pressure and arterial stiffness in patients with essential hypertension

R Soanker, MUR Naidu, SB Raju… - Indian journal of …, 2012 - journals.lww.com
Materials and Methods: In this single arm, open-labeled study, 13 patients were given
nebivolol, 5 mg orally once daily for 15 days. Primary outcome was change in central aortic …

A pharmacokinetic drug interaction study between nebivolol and paroxetine in healthy volunteers

C Briciu, M Neag, D Muntean, L Vlase… - Journal of clinical …, 2014 - Wiley Online Library
What is known and objective Nebivolol is a highly selective beta‐blocker with additional
vasodilator properties, widely used in the clinical practice for the treatment of hypertension …

Both morning and evening dosing of nebivolol reduces trough mean blood pressure surge in hypertensive patients

MC Acelajado, R Pisoni, T Dudenbostel… - Journal of the American …, 2012 - Elsevier
The morning blood pressure surge (MBPS) has been shown to be an independent predictor
of cardiovascular events. There is insufficient evidence on the effect of nebivolol, a …

Nebivolol for the treatment of essential systemic arterial hypertension: a systematic review and meta-analysis

VB Seleme, GL Marques, AEM Mendes, I Rotta… - American Journal of …, 2021 - Springer
Introduction Cardiovascular diseases are the main cause of mortality worldwide, and
systemic arterial hypertension is associated with a large number of these cases. The …

Pulmonary effects of nebivolol

R Dal Negro - Therapeutic advances in cardiovascular …, 2009 - journals.sagepub.com
The pharmacological control of arterial hypertension is a very frequent issue in clinical
practice and some critical aspects can arise in particular circumstances and with particular …