[HTML][HTML] RNF126, 168 and CUL1: The Potential Utilization of Multi-Functional E3 Ubiquitin Ligases in Genome Maintenance for Cancer Therapy
HR Chang - Biomedicines, 2023 - mdpi.com
Ubiquitination is a post-translational modification (PTM) that is involved in proteolysis,
protein–protein interaction, and signal transduction. Accumulation of mutations and genomic …
protein–protein interaction, and signal transduction. Accumulation of mutations and genomic …
[HTML][HTML] PREX2 contributes to radiation resistance by inhibiting radiotherapy-induced tumor immunogenicity via cGAS/STING/IFNs pathway in colorectal cancer
M Li, J Xiao, S Song, F Han, H Liu, Y Lin, Y Ni, S Zeng… - BMC medicine, 2024 - Springer
Background Colorectal cancer (CRC) lacks established biomarkers or molecular targets for
predicting or enhancing radiation response. Phosphatidylinositol-3, 4, 5-triphosphate …
predicting or enhancing radiation response. Phosphatidylinositol-3, 4, 5-triphosphate …
[HTML][HTML] Brain intratumoural astatine-211 radiotherapy targeting syndecan-1 leads to durable glioblastoma remission and immune memory in female mice
L Roncali, S Marionneau-Lambot, C Roy, R Eychenne… - eBioMedicine, 2024 - Elsevier
Background Glioblastoma (GB), the most aggressive brain cancer, remains a critical clinical
challenge due to its resistance to conventional treatments. Here, we introduce a …
challenge due to its resistance to conventional treatments. Here, we introduce a …
[HTML][HTML] New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling
OV Salomatina, TE Kornienko, AL Zakharenko… - Molecules, 2024 - mdpi.com
Deoxycholic acid derivatives containing various heterocyclic functional groups at C-3 on the
steroid scaffold were designed and synthesized as promising dual tyrosyl-DNA …
steroid scaffold were designed and synthesized as promising dual tyrosyl-DNA …
The determination of fibroblast and keratinocyte death types after their transplantation into γ-irradiated porous scaffold in vitro
In the course of radiation therapy, normal cells surrounding the tumor are also irradiated.
During and after irradiation, they undergo a series of structural and metabolic changes …
During and after irradiation, they undergo a series of structural and metabolic changes …
[图书][B] Radiopharmaceutical Therapy for Tumor Immunomodulation and Enhancing Immunotherapy Response
CPA Kerr - 2024 - search.proquest.com
Fifty percent of all cancer patients receive radiation therapy as a component of treatment.
Radiation can immunomodulate the tumor microenvironment through a variety of …
Radiation can immunomodulate the tumor microenvironment through a variety of …
ラジオセラノスティクスを目的とした放射性薬剤の開発
小川数馬 - ファルマシア, 2023 - jstage.jst.go.jp
抄録 ラジオセラノスティクスとは放射性同位元素 (Radioisotope) と治療 (Therapeutics) と診断
(Diagnosis) を組み合わせた造語である. ラジオセラノスティクスでは, 同等の体内動態を示す診断 …
(Diagnosis) を組み合わせた造語である. ラジオセラノスティクスでは, 同等の体内動態を示す診断 …