[HTML][HTML] Genome editing: an essential technology for cancer treatment

M Tufail - Medicine in Omics, 2022 - Elsevier
When genetic engineering was first developed in the 1970s, it opened new possibilities for
genome editing. The life sciences have reaped numerous gains from gene-editing …

CZT-1 Is a Novel Transcription Factor Controlling Cell Death and Natural Drug Resistance in Neurospora crassa

AP Gonçalves, C Hall, DJ Kowbel… - G3: Genes …, 2014 - academic.oup.com
We pinpoint CZT-1 (cell death–activated zinc cluster transcription factor) as a novel
transcription factor involved in tolerance to cell death induced by the protein kinase inhibitor …

Activation of a TRP-like channel and intracellular Ca2+ dynamics during phospholipase-C-mediated cell death

AP Goncalves, JM Cordeiro, J Monteiro… - Journal of Cell …, 2014 - journals.biologists.com
The model organism Neurospora crassa undergoes programmed cell death when exposed
to staurosporine. Here, we show that staurosporine causes defined changes in cytosolic free …

[HTML][HTML] Involvement of mitochondrial proteins in calcium signaling and cell death induced by staurosporine in Neurospora crassa

AP Gonçalves, JM Cordeiro, J Monteiro… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Staurosporine-induced cell death in Neurospora crassa includes a well defined sequence of
alterations in cytosolic calcium levels, comprising extracellular Ca 2+ influx and mobilization …

[HTML][HTML] Extracellular calcium triggers unique transcriptional programs and modulates staurosporine-induced cell death in Neurospora crassa

AP Gonçalves, J Monteiro, C Lucchi, DJ Kowbel… - Microbial Cell, 2014 - ncbi.nlm.nih.gov
Alterations in the intracellular levels of calcium are a common response to cell death stimuli
in animals and fungi and, particularly, in the Neurospora crassa response to staurosporine …

6 Heterogenic Incompatibility in Fungi

K Esser - Growth, Differentiation and Sexuality, 2016 - Springer
In biology, incompatibility is usually defined as restriction of mating competence controlled
by genes other than those determining sexual differentiation. It has been long recognised …

[PDF][PDF] Medicine in Omics

M Tufail - researchgate.net
When genetic engineering was first developed in the 1970s, it opened new possibilities for
genome editing. The life sciences have reaped numerous gains from gene‐editing …

[PDF][PDF] Study of the effect of heavy metals and differences of light/dark cycle in the melatonin hormone protein Clock and growth of Neurospora crassa fungi. Revis …

N Al-Sardar, M Ibrahim Khalil - 2022 - revistabionatura.com
It was using Neurospora crassa as a model organism to study the biological clock. Due to its
use for more than 50 years in the circadian rhythm Study, this biological cycle has been …

[HTML][HTML] Correlation between physical characteristics of the indoor environment toward the concentration of fungi in the inpatient rooms of dr. Soebandi Regional …

SMZ El Hamzah, A Setyawardani… - Public Health and …, 2020 - ww.phpmajournal.org
Background and purpose: Air quality is an important determinant of a healthy life. One
indicator of air pollutants in the room is fungi, which in hospital setting may cause …

A new mutant of Neurospora crassa (VU-82) having defects in branching and tip growth.

M Anita, V Alka, V Harish - Journal of Environmental Research and …, 2015 - cabdirect.org
A growth defective mutant of Neurospora crassa, VU-82 was generated in the laboratory by
mutagenizing conidia of well characterized strain of N. crassa (FGSC 2489) using Ethyl …