Organophosphorus (OP) pesticides and nerve agents still pose a threat to the population.
Treatment of OP poisoning is an ongoing challenge and burden for medical services …

The present article reviews published efforts to study acetylcholinesterase and
butyrylcholinesterase structure and function using computer-based modeling and simulation …

Structural information of butyrylcholinesterase (BChE) and its variants associated with
several diseases are discussed here. Pure human BChE has been proved safe and effective …

The aim of the study was to evaluate the neuroprotective function of sea cucumber ovum
peptide-derived NDEELNK and explore the underlying molecular mechanisms. NDEELNK …

In this study, S‐(Acyloxy) butyl‐N, N‐Diethyldithiocarbamate compounds (P1‐P7) were
synthesized by s‐alkylation of N, N‐diethyldithiocarbamate sodium trihydrate with 4 …

A new series of pyrazole, phenylpyrazole, and pyrazoline analogs of diarylpentanoids
(excluding compounds 3a, 4a, 5a, and 5b) was pan‐assay interference compounds‐filtered …

Nerve agents pose significant threats to civilian and military populations. The reactivation of
acetylcholinesterase (AChE) is critical in treating acute poisoning, but there is still lacking …

Organophosphorus Compounds (OPCs) are used as pesticides to control pest, as chemical
weapons in military conflict and unfortunately in the terrorist attack. These compounds are …

High lethality, fast action, and simple synthesis make nerve agents (NAs) the most dreaded
chemical weapons (CWs) of mass destruction in the world. Disturbances of the autonomic …

In this communication, we report the synthesis and cholinesterase (ChE)/monoamine
oxidase (MAO) inhibition of 19 quinolinones (QN1-19) and 13 dihydroquinolinones (DQN1 …