Plant natural products (PNPs) are specialized metabolites with diverse bioactivities. They
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …

Covering: 2011–2022 The low amounts of terpenoids produced in plants and the difficulty in
synthesizing these complex structures have stimulated the production of terpenoid …

Advances in synthetic biology enable microbial hosts to synthesize valuable natural
products in an efficient, cost-competitive and safe manner. However, current engineering …

Current approaches for the production of high-value compounds in microorganisms mostly
use the cytosol as a general reaction vessel. However, competing pathways and metabolic …

Metabolic engineering approaches for the production of high-value chemicals in
microorganisms mostly use the cytosol as general reaction vessel. However, sequestration …

Harnessing mitochondria is considered as a promising method for biosynthesis of terpenes
due to the adequate supply of acetyl-CoA and redox equivalents in mitochondria. However …

Eukaryotic yeasts have a variety of subcellular compartments and are ideal platform strains
for the construction of complex heterologous natural product biosynthesis pathways …

Methanol is an ideal feedstock for chemical and biological manufacturing. Constructing an
efficient cell factory is essential for producing complex compounds through methanol …

Limonene and its derivatives have great market potential with diverse applications in food,
pharmaceuticals, cosmetics, etc. Commercial production of limonene and its derivatives …

Establishing efficient synthetic pathways for microbial production of biochemicals is often
hampered by competing pathways and insufficient precursor supply. Compartmentalization …