Novel tigecycline resistance mechanisms in Acinetobacter baumannii mediated by mutations in adeS, rpoB and rrf

X Hua, J He, J Wang, L Zhang, L Zhang… - Emerging Microbes & …, 2021 - Taylor & Francis
Acinetobacter baumannii is an important pathogen in hospital acquired infections. Although
tigecycline currently remains a potent antibiotic for treating infections caused by multidrug …

Biocides used as material preservatives modify rates of de novo mutation and horizontal gene transfer in bacteria

SBI Schmidt, A Rodríguez-Rojas, J Rolff… - Journal of hazardous …, 2022 - Elsevier
Antimicrobial resistance (AMR) is a global health problem with the environment being an
important compartment for the evolution and transmission of AMR. Previous studies showed …

The Effect of β-Lactam Antibiotics on the Evolution of Ceftazidime/Avibactam and Cefiderocol Resistance in KPC-Producing Klebsiella pneumoniae

P Zhang, H Hu, Q Shi, L Sun, X Wu, X Hua… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
In this study, we aimed to clarify the evolutionary trajectory of a Klebsiella pneumoniae
carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-Kp) population during β …

Genes and Proteomes Associated With Increased Mutation Frequency and Multidrug Resistance of Naturally Occurring Mismatch Repair-Deficient Salmonella …

H Sheng, J Huang, Z Han, M Liu, Z Lü… - Frontiers in …, 2020 - frontiersin.org
The emergence of antibiotic-resistant Salmonella through mutations led to mismatch repair
(MMR) deficiency that represents a potential hazard to public health. Here, four …

Trends in the Use of Proper Methods for Estimating Mutation Rates in Fluctuation Experiments

GA Devin, A Couce - Axioms, 2023 - mdpi.com
The accurate quantification of mutation rates holds significance across diverse fields,
including evolution, cancer research, and antimicrobial resistance. Eighty years ago, Luria …

Isolation and Genomics of multidrug-resistant Brevundimonas diminuta collected from patients with pertussis-like symptoms

A Safarchi, VS Nikbin, S Saedi, M Dinarvand… - bioRxiv, 2021 - biorxiv.org
Brevundinomas diminuta is known as an opportunistic pathogen and is rarely associated
with invasive infections in humans causing infection in the different parts of the body. In this …