[HTML][HTML] A potential new pathway for heparin treatment of sepsis-induced lung injury: inhibition of pulmonary endothelial cell pyroptosis by blocking hMGB1-LPS …
R Yang, X Zhang - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Sepsis is a significant cause of mortality in critically ill patients. Acute lung injury (ALI) is a
leading cause of death in these patients. During sepsis, infiltration of protein-rich …
leading cause of death in these patients. During sepsis, infiltration of protein-rich …
Targeting the host response in sepsis: current approaches and future evidence
Sepsis, a dysregulated host response to infection characterized by organ failure, is one of
the leading causes of death worldwide. Disbalances of the immune response play an …
the leading causes of death worldwide. Disbalances of the immune response play an …
Immunomodulatory effects of macrolides considering evidence from human and veterinary medicine
JM Blondeau - Microorganisms, 2022 - mdpi.com
Macrolide antimicrobial agents have been in clinical use for more than 60 years in both
human and veterinary medicine. The discovery of the non-antimicrobial properties of …
human and veterinary medicine. The discovery of the non-antimicrobial properties of …
Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1
K Peukert, F Steinhagen, M Fox, C Feuerborn… - Respiratory …, 2022 - Springer
Background Inhalation of dust containing silica particles is associated with severe
pulmonary inflammation and lung injury leading to chronic silicosis including fibrotic …
pulmonary inflammation and lung injury leading to chronic silicosis including fibrotic …
Modulation of the Acute Inflammatory Response Induced by the Escherichia coli Lipopolysaccharide through the Interaction of Pentoxifylline and Florfenicol in a …
V Cazanga, C Palma, T Casanova, D Rojas, K Barrera… - Antibiotics, 2023 - mdpi.com
Background: Experimental reports have demonstrated that florfenicol (FFC) exerts potent
anti-inflammatory effects, improving survival in a murine endotoxemia model. Considering …
anti-inflammatory effects, improving survival in a murine endotoxemia model. Considering …
Colitis induced by IL-17A-inhibitors
L Grümme, S Dombret, T Knösel, A Skapenko… - Clinical Journal of …, 2024 - Springer
Abstract Background Interleukin (IL)-17A is essential for intestinal mucosal integrity,
contributing to the prevention of detrimental immunity such as infectious colitis and …
contributing to the prevention of detrimental immunity such as infectious colitis and …
[HTML][HTML] Green tea extract reduced lipopolysaccharide-induced inflammation in L2 cells as acute respiratory distress syndrome model through genes and cytokine pro …
D Priyandoko, W Widowati, L Lenny… - Avicenna Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Acute Respiratory Distress Syndrome (ARDS) is a severe lung inflammatory
condition that has the capacity to impair gas exchange and lead to hypoxemia. This …
condition that has the capacity to impair gas exchange and lead to hypoxemia. This …
[HTML][HTML] Cyclic Phytosphingosine-1-Phosphate Primed Mesenchymal Stem Cells Ameliorate LPS-Induced Acute Lung Injury in Mice
Y Park, J Jang, J Lee, H Baek, J Park… - … Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
Methods and Results cP1P treatment significantly stimulated MSC migration and invasion
ability. In cytokine array, secretion of vascular-related factors was increased in cP1P primed …
ability. In cytokine array, secretion of vascular-related factors was increased in cP1P primed …
The Interplay between Antibiotics and the Host Immune Response in Sepsis: From Basic Mechanisms to Clinical Considerations: A Comprehensive Narrative Review
M Tosi, I Coloretti, M Meschiari, S De Biasi, M Girardis… - Antibiotics, 2024 - mdpi.com
Sepsis poses a significant global health challenge due to immune system dysregulation.
This narrative review explores the complex relationship between antibiotics and the immune …
This narrative review explores the complex relationship between antibiotics and the immune …
Dual functional therapeutics: mitigating bacterial infection and associated inflammation
The emergence of antimicrobial resistance, coupled with the occurrence of persistent
systemic infections has already complicated clinical therapy efforts. Moreover, infections are …
systemic infections has already complicated clinical therapy efforts. Moreover, infections are …