Crystalloid infusion is widely employed in patient care for volume replacement and
resuscitation. In the United States the crystalloid of choice is often normal saline. Surgeons …

Background Rapid fluid administration may decrease hemoglobin concentration (Hb) by a
diluting effect, which could limit the increase in oxygen delivery (DO2) expected with a …

BACKGROUND. Iron bioavailability has been identified as a factor that influences cellular
hypoxia sensing, putatively via an action on the hypoxia-inducible factor (HIF) pathway. We …

BACKGROUND There are multiple approaches to the blood product and fluid resuscitation
of a bleeding trauma patient. An in silico model of different trauma resuscitation strategies …

Recently, buffered salt solutions and 20% albumin (small volume resuscitation) have been
advocated as an alternative fluid for intravenous resuscitation. The relative comparative …

Administration of bolus intravenous fluid is associated with respiratory dysfunction and
increased mortality, findings with no clear mechanistic explanation. The objective of this …

Sepsis is a leading cause of morbidity and mortality in children with a worldwide prevalence
in pediatric intensive care units of approximately 8%. Fluid bolus therapy (FBT) is a first line …

An aneurysmal subarachnoid hemorrhage (aSAH) is a devastating event associated with a
high mortality and morbidity rate. Though numerous medications are used to prevent …

Objective The aim of the present paper is to study the indications for fluid bolus therapy
(FBT) and its associated physiological changes in ED patients. Methods Prospective …

Background: Inadvertent fluid loading—and resultant sodium and chloride—is common in
critically ill patients. Sources such as fluid used as vehicles for drug infusions and boluses …