SARS-CoV-2-specific immune response and the pathogenesis of COVID-19
E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
SARS-CoV-2 and the host cell: a tale of interactions
M Pizzato, C Baraldi, G Boscato Sopetto… - Frontiers in …, 2022 - frontiersin.org
The ability of a virus to spread between individuals, its replication capacity and the clinical
course of the infection are macroscopic consequences of a multifaceted molecular …
course of the infection are macroscopic consequences of a multifaceted molecular …
Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1
J Chai, Y Cai, C Pang, L Wang, S McSweeney… - Nature …, 2021 - nature.com
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has created global health and
economic emergencies. SARS-CoV-2 viruses promote their own spread and virulence by …
economic emergencies. SARS-CoV-2 viruses promote their own spread and virulence by …
Viroporins: Structure, function, and their role in the life cycle of SARS-CoV-2
Viroporins are indispensable for viral replication. As intracellular ion channels they disturb
pH gradients of organelles and allow Ca 2+ flux across ER membranes. Viroporins interact …
pH gradients of organelles and allow Ca 2+ flux across ER membranes. Viroporins interact …
[HTML][HTML] SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development
S Zhou, P Lv, M Li, Z Chen, H Xin, S Reilly… - Biomedicine & …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating
global pandemic, which has seriously affected human health worldwide. The discovery of …
global pandemic, which has seriously affected human health worldwide. The discovery of …
COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy
As the COVID-19 pandemic continues into its third year, emerging data indicates increased
risks associated with SARS-CoV-2 infection during pregnancy, including pre-eclampsia …
risks associated with SARS-CoV-2 infection during pregnancy, including pre-eclampsia …
pH-and calcium-dependent aromatic network in the SARS-CoV-2 envelope protein
The envelope (E) protein of the SARS-CoV-2 virus is a membrane-bound viroporin that
conducts cations across the endoplasmic reticulum Golgi intermediate compartment …
conducts cations across the endoplasmic reticulum Golgi intermediate compartment …
[HTML][HTML] Endocytosis and transcytosis of SARS-CoV-2 across the intestinal epithelium and other tissue barriers
E Knyazev, S Nersisyan, A Tonevitsky - Frontiers in immunology, 2021 - frontiersin.org
Since 2003, the world has been confronted with three new betacoronaviruses that cause
human respiratory infections: SARS-CoV, which causes severe acute respiratory syndrome …
human respiratory infections: SARS-CoV, which causes severe acute respiratory syndrome …
Distinct motifs in the E protein are required for SARS-CoV-2 virus particle formation and lysosomal deacidification in host cells
K Miura, Y Suzuki, K Ishida, M Arakawa, H Wu… - Journal of …, 2023 - Am Soc Microbiol
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a major public health
concern, but the mechanisms underlying its viral particle formation are not well understood …
concern, but the mechanisms underlying its viral particle formation are not well understood …
Airway epithelial cell junctions as targets for pathogens and antimicrobial therapy
Intercellular contacts between epithelial cells are established and maintained by the apical
junctional complexes (AJCs). AJCs conserve cell polarity and build epithelial barriers to …
junctional complexes (AJCs). AJCs conserve cell polarity and build epithelial barriers to …