Reactive oxygen species and cancer paradox: to promote or to suppress?
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …
increasingly being appreciated as powerful signaling molecules involved in the regulation of …
Advances on natural polyphenols as anticancer agents for skin cancer
S Sajadimajd, R Bahramsoltani, A Iranpanah… - Pharmacological …, 2020 - Elsevier
Polyphenols are one of most important phytochemicals distributing in herb plants,
vegetables and fruits, which known as important anticancer agents. Given the high …
vegetables and fruits, which known as important anticancer agents. Given the high …
Molecular targets of dietary agents for prevention and therapy of cancer
BB Aggarwal, S Shishodia - Biochemical pharmacology, 2006 - Elsevier
While fruits and vegetables are recommended for prevention of cancer and other diseases,
their active ingredients (at the molecular level) and their mechanisms of action less well …
their active ingredients (at the molecular level) and their mechanisms of action less well …
Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies
BB Aggarwal, A Bhardwaj, RS Aggarwal… - Anticancer …, 2004 - ar.iiarjournals.org
Resveratrol, trans-3, 5, 4'-trihydroxystilbene, was first isolated in 1940 as a constituent of the
roots of white hellebore (Veratrum grandiflorum O. Loes), but has since been found in …
roots of white hellebore (Veratrum grandiflorum O. Loes), but has since been found in …
Pathophysiological consequences of VEGF-induced vascular permeability
SM Weis, DA Cheresh - Nature, 2005 - nature.com
Although vascular endothelial growth factor (VEGF) induces angiogenesis, it also disrupts
vascular barrier function in diseased tissues. Accordingly, VEGF expression in cancer and …
vascular barrier function in diseased tissues. Accordingly, VEGF expression in cancer and …
Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy
M Ushio-Fukai, Y Nakamura - Cancer letters, 2008 - Elsevier
Angiogenesis is essential for tumor growth, metastasis, arteriosclerosis as well as embryonic
development and wound healing. Its process is dependent on cell proliferation, migration …
development and wound healing. Its process is dependent on cell proliferation, migration …
Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: a potentially protective …
E Scoditti, N Calabriso, M Massaro, M Pellegrino… - Archives of biochemistry …, 2012 - Elsevier
Diets with high content of antioxidant polyphenols are associated with low prevalence of
cardiovascular diseases and cancer. Inflammatory angiogenesis is a key pathogenic …
cardiovascular diseases and cancer. Inflammatory angiogenesis is a key pathogenic …
New insights on the anticancer properties of dietary polyphenols
P Fresco, F Borges, C Diniz… - Medicinal research …, 2006 - Wiley Online Library
Cancer, one of the major causes of death across the world, has shown to be a largely
preventable disease, highly susceptible to modulation by dietary factors. Phenolic …
preventable disease, highly susceptible to modulation by dietary factors. Phenolic …
Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms
M Athar, JH Back, L Kopelovich, DR Bickers… - Archives of biochemistry …, 2009 - Elsevier
Plant-derived polyphenolic compounds, such as the stilbene resveratrol (trans-3, 4′, 5-
trihydroxystilbene), have been identified as potent anti-cancer agents. Extensive in vitro …
trihydroxystilbene), have been identified as potent anti-cancer agents. Extensive in vitro …
Cardiovascular protective effects of resveratrol
S Bradamante, L Barenghi… - Cardiovascular drug …, 2004 - Wiley Online Library
ABSTRACT Resveratrol (3, 4′, 5‐trihydroxy‐trans‐stilbene), a phytoalexin found in grape
skins, peanuts, and red wine, has been reported to have a wide range of biological and …
skins, peanuts, and red wine, has been reported to have a wide range of biological and …