Longitudinal association between Body mass index (BMI), BMI trajectories and the risk of frailty among older adults: a systematic review and meta-analysis of …

Q Sun, X Xia, F He - Archives of gerontology and geriatrics, 2024 - Elsevier
Objective We aimed to determine whether BMI categories and BMI trajectories were
longitudinally associated with frailty in older adults via systematic review and meta-analysis …

Factors associated with frailty in older adults in community and nursing home settings: A systematic review with a meta-analysis

J Liu, Y Zhu, JK Tan, AH Ismail, R Ibrahim… - Journal of Clinical …, 2024 - mdpi.com
Background: Frailty is a globally recognized issue. However, there is a lack of evidence
exploring factors associated with frailty among older residents in community and nursing …

The brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression

R Jiang, S Noble, M Rosenblatt, W Dai, J Ye… - Nature …, 2024 - nature.com
Cross-sectional studies have demonstrated strong associations between physical frailty and
depression. However, the evidence from prospective studies is limited. Here, we analyze …

Frailty and psychiatric disorders: A bidirectional Mendelian randomization study

JH Chen, H Lei, YF Wan, XC Zhu, LY Zeng… - Journal of Affective …, 2024 - Elsevier
Background The association between frailty and psychiatric disorders has been reported in
observational studies. However, it is unclear whether frailty facilitates the appearance of …

Association of phenotypic frailty and frailty index with type 2 diabetes and dyslipidemia in middle-aged and elderly Chinese: A longitudinal cohort study

LL Ma, N Chen, Y Zhang, XM Feng, M Gong… - Archives of gerontology …, 2024 - Elsevier
Purpose Frailty, type 2 diabetes (T2D) and dyslipidemia are highly prevalent in middle-aged
and elderly populations. However, evidence on the longitudinal association of frailty with …

Blood lipid levels mediating the effects of sex hormone-binding globulin on coronary heart disease: Mendelian randomization and mediation analysis

J Yang, J Zhou, H Liu, J Hao, S Hu, P Zhang, H Wu… - Scientific Reports, 2024 - nature.com
Observational studies indicate that serum sex hormone-binding globulin (SHBG) levels are
inversely correlated with blood lipid levels and coronary heart disease (CHD) risk. Given that …

[HTML][HTML] Genetic and phenotypic associations of frailty with cardiovascular indicators and behavioral characteristics

Y Chen, S Lin, S Yang, M Qi, Y Ren, C Tian… - Journal of Advanced …, 2024 - Elsevier
Abstract Introduction Frailty Index (FI) is a common measure of frailty, which has been
advocated as a routine clinical test by many guidelines. The genetic and phenotypic …

Impact of menopause-associated frailty on traumatic brain injury

SB Sinder, SV Sharma, IS Shirvaikar… - Neurochemistry …, 2024 - Elsevier
Navigating menopause involves traversing a complex terrain of hormonal changes that
extend far beyond reproductive consequences. Menopausal transition is characterized by a …

Causal role of immune cells in major depressive disorder and bipolar disorder: Mendelian randomization (MR) study

Y Zhang, SW Wang, J Ding, X Wen, T Li, L Yang… - Journal of Affective …, 2024 - Elsevier
Background Major depressive disorder (MDD) and bipolar disorder (BD) are prevalent
psychiatric conditions linked to inflammatory processes. However, it is unclear whether …

Dietary Factors and the Risk of Depression among Women with Polycystic Ovary Syndrome

K Łagowska, J Bajerska, JM Pieczyńska-Zając - Nutrients, 2024 - mdpi.com
This study aimed to assess the association between dietary factors and depression in a
group of polycystic ovary syndrome (PCOS) women and to evaluate potential interactions …