Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Protocatechuic acid is a natural phenolic acid, which widely exists in our daily diet and
herbs. It is also one of the main metabolites of complex polyphenols, such as anthocyanins …

Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …

Metformin, a well‐known AMPK agonist, has been widely used as the first‐line drug for
treating type 2 diabetes. There had been a significant concern regarding the use of …

The renin–angiotensin system (RAS) is undisputedly well-studied as one of the oldest and
most critical regulators for arterial blood pressure, fluid volume, as well as renal function. In …

Atherosclerosis (AS) is a chronic disease with a complex pathology that may lead to several
cardiovascular and cerebrovascular diseases; however, further research is necessary to …

Abstract Knowledge gaps that limit the development of therapies for polycystic ovary
syndrome (PCOS) concern various environmental factors that impact clinical characteristics …

Over the past 66 years, our knowledge of the role of the endothelium in the regulation of
cardiovascular function and dysfunction has advanced from the assumption that it is a single …

Oxidized low‑density lipoprotein (ox‑LDL)‑induced endothelial damage contributes to the
initiation and pathogenesis of atherosclerosis. Salidroside can alleviate atherosclerosis and …

The Mediterranean diet has long been recognized as one of the most effective ways to
prevent and improve cardiovascular disease. Extra virgin olive oil (EVOO) is the typical …