[HTML][HTML] Arctium lappa leaves based on network pharmacology and experimental validation attenuate atherosclerosis by targeting the AMPK-mediated PPARG/LXRα …
M Wang, B Cui, M Gong, Q Liu, X Zhuo, J Lv… - Biomedicine & …, 2022 - Elsevier
Arctium lappa (A. lappa) leaves are widely used in various traditional Chinese herbal
formulae to ameliorate atherosclerosis (AS) and its complications such as stroke; however …
formulae to ameliorate atherosclerosis (AS) and its complications such as stroke; however …
[HTML][HTML] Salidroside attenuates oxidized low‑density lipoprotein‑induced endothelial cell injury via promotion of the AMPK/SIRT1 pathway
D Zhao, X Sun, S Lv, M Sun, H Guo… - International …, 2019 - spandidos-publications.com
Oxidized low‑density lipoprotein (ox‑LDL)‑induced endothelial damage contributes to the
initiation and pathogenesis of atherosclerosis. Salidroside can alleviate atherosclerosis and …
initiation and pathogenesis of atherosclerosis. Salidroside can alleviate atherosclerosis and …
AMPK is associated with the beneficial effects of antidiabetic agents on cardiovascular diseases
Diabetics have higher morbidity and mortality in cardiovascular disease (CVD). A variety of
antidiabetic agents are available for clinical choice. Cardiovascular (CV) safety assessment …
antidiabetic agents are available for clinical choice. Cardiovascular (CV) safety assessment …
[HTML][HTML] Gip as a potential therapeutic target for atherosclerotic cardiovascular disease–a systematic review
Y Mori, T Matsui, T Hirano, S Yamagishi - International Journal of …, 2020 - mdpi.com
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1)
are gut hormones that are secreted from enteroendocrine L cells and K cells in response to …
are gut hormones that are secreted from enteroendocrine L cells and K cells in response to …
[HTML][HTML] Substances of interest that support glaucoma therapy
SC Saccà, P Corazza, S Gandolfi, D Ferrari, S Sukkar… - Nutrients, 2019 - mdpi.com
Glaucoma is a multifactorial disease in which pro-apoptotic signals are directed to retinal
ganglion cells. During this disease the conventional outflow pathway becomes …
ganglion cells. During this disease the conventional outflow pathway becomes …
Role of AMP-activated protein kinase on cardio-metabolic abnormalities in the development of diabetic cardiomyopathy: a molecular landscape
Cardiovascular complications associated with diabetes mellitus remains a leading cause of
morbidity and mortality across the world. Diabetic cardiomyopathy is a descriptive pathology …
morbidity and mortality across the world. Diabetic cardiomyopathy is a descriptive pathology …
[HTML][HTML] Naringenin ameliorates homocysteine induced endothelial damage via the AMPKα/Sirt1 pathway
H Li, L Liu, Z Cao, W Li, R Liu, Y Chen, C Li… - Journal of Advanced …, 2021 - Elsevier
Introduction Endothelial damage (ED) has been implicated in accelerating the development
of atherosclerosis. The latter condition is a risk factor for developing several cardiovascular …
of atherosclerosis. The latter condition is a risk factor for developing several cardiovascular …
[HTML][HTML] Vasculoprotective effects of vildagliptin. Focus on atherogenesis
M Wiciński, K Górski, E Wódkiewicz, M Walczak… - International journal of …, 2020 - mdpi.com
Vildagliptin is a representative of Dipeptidyl Peptidase-4 (DPP-4) inhibitors,
antihyperglycemic drugs, approved for use as monotherapy and combination therapy in type …
antihyperglycemic drugs, approved for use as monotherapy and combination therapy in type …
Telmisartan attenuates obesity-induced insulin resistance via suppression of AMPK mediated ER stress
Y Huang, Y Li, Q Liu, J Zhang, Z Zhang, T Wu… - Biochemical and …, 2020 - Elsevier
Telmisartan is a known angiotensin II (Ang II) AT1 receptor blocker (ARB). While the
beneficial effect of Telmisartan on glucose and lipid metabolism has been reported, the …
beneficial effect of Telmisartan on glucose and lipid metabolism has been reported, the …
MiRNA-122-5p inhibitor abolishes angiotensin II–mediated loss of autophagy and promotion of apoptosis in rat cardiofibroblasts by modulation of the apelin-AMPK …
M Yang, JJ Song, XC Yang, GZ Zhong… - In Vitro Cellular & …, 2022 - Springer
MicroRNAs (miRNAs) have emerged as essential regulators that could have pivotal roles in
cardiac homeostasis and pathological remodeling of various cardiovascular diseases. We …
cardiac homeostasis and pathological remodeling of various cardiovascular diseases. We …