Inflammation is a defensive response of the organism to traumatic, infectious, toxic,
ischemic, and autoimmune injury. Inflammatory mediators are released to effectively …

Perivascular adipose tissue (PVAT) has been identified to have significant endocrine and
paracrine functions, such as releasing bioactive adipokines, cytokines, and chemokines …

Atherosclerotic cardiovascular diseases, commonly known as the formation of fibrofatty
lesions in the artery wall, are the leading causes of death globally. Oxidized low-density …

Ginkgolide B (GB), the diterpenoid lactone compound isolated from the extracts of Ginkgo
biloba leaves, significantly improves cognitive impairment, but its potential pharmacological …

Increasing evidences have confirmed that long non-coding RNA LOXL1-AS1 functions in
multiple human diseases. Here, we aim to explore the function and mechanism of LOXL1 …

Cardiovascular diseases (CVDs) and neurodegenerative disorders, such as diabetes
mellitus and Alzheimer's disease, share a common pathophysiological link involving insulin …

Atherosclerosis, in general, is an age-associated cardiovascular disease wherein a
progressive decline in mitochondrial function due to aging majorly contributes to the disease …

Endothelial mitochondria play important signaling roles critical for the regulation of various
cellular processes, including calcium signaling, ROS generation, NO synthesis or …

Glucose-dependent insulinotropic polypeptide (GIP) has been reported to have an
atheroprotective property in animal models. However, the effect of GIP on macrophage foam …

Background The effects of trans-chalcone on atherosclerosis and NAFLD have been
investigated. However, the underlying molecular mechanisms of these effects are not …