Context-specific regulation of extracellular vesicle biogenesis and cargo selection
AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …
other cells. An important aspect of cell–cell communication involves secretion of molecules …
Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
QF Han, WJ Li, KS Hu, J Gao, WL Zhai, JH Yang… - Molecular cancer, 2022 - Springer
Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …
various physiological and pathological processes. Their biogenesis involves four key steps …
Molecular mediators of RNA loading into extracellular vesicles
C Corrado, MM Barreca, C Zichittella, R Alessandro… - Cells, 2021 - mdpi.com
In the last decade, an increasing number of studies have demonstrated that non-coding
RNA (ncRNAs) cooperate in the gene regulatory networks with other biomolecules …
RNA (ncRNAs) cooperate in the gene regulatory networks with other biomolecules …
Mechanisms controlling microRNA expression in tumor
S Chen, Y Wang, D Li, H Wang, X Zhao, J Yang… - Cells, 2022 - mdpi.com
MicroRNAs (miRNAs) are widely present in many organisms and regulate the expression of
genes in various biological processes such as cell differentiation, metabolism, and …
genes in various biological processes such as cell differentiation, metabolism, and …
The role of non-coding RNAs in extracellular vesicles in breast cancer and their diagnostic implications
M Samuels, W Jones, B Towler, C Turner, S Robinson… - Oncogene, 2023 - nature.com
Breast Cancer (BC) is the most common form of cancer worldwide, responsible for 25% of
cancers in women. Whilst treatment is effective and often curative in early BC, metastatic …
cancers in women. Whilst treatment is effective and often curative in early BC, metastatic …
The role and applications of extracellular vesicles in osteoporosis
F Fang, J Yang, J Wang, T Li, E Wang, D Zhang, X Liu… - Bone research, 2024 - nature.com
Osteoporosis is a widely observed condition characterized by the systemic deterioration of
bone mass and microarchitecture, which increases patient susceptibility to fragile fractures …
bone mass and microarchitecture, which increases patient susceptibility to fragile fractures …
Tumor-derived miR-378a-3p-containing extracellular vesicles promote osteolysis by activating the Dyrk1a/Nfatc1/Angptl2 axis for bone metastasis
J Wang, X Du, X Wang, H Xiao, N Jing, W Xue, B Dong… - Cancer letters, 2022 - Elsevier
Most prostate cancer (PCa)-related deaths are caused by progression to bone metastasis.
Recently, the importance of extracellular vesicles (EVs) in pre-metastatic niche formation …
Recently, the importance of extracellular vesicles (EVs) in pre-metastatic niche formation …
Advances in purification, modification, and application of extracellular vesicles for novel clinical treatments
Y Matsuzaka, R Yashiro - Membranes, 2022 - mdpi.com
Extracellular vesicles (EV) are membrane vesicles surrounded by a lipid bilayer membrane
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …
Cancer-derived exosomes as novel biomarkers in metastatic gastrointestinal cancer
D Zhong, Z Wang, Z Ye, Y Wang, X Cai - Molecular Cancer, 2024 - Springer
Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor
and has a significant impact on mortality rates. Nevertheless, the swift advancement of …
and has a significant impact on mortality rates. Nevertheless, the swift advancement of …
[HTML][HTML] Exploring the roles and molecular mechanisms of RNA binding proteins in the sorting of noncoding RNAs into exosomes during tumor progression
T Wang, H Zhang - Journal of Advanced Research, 2023 - Elsevier
Background RNA binding proteins (RBPs) play a role in sorting non-coding RNAs (ncRNAs)
into exosomes. These ncRNAs, carried by exosomes, are involved in regulating various …
into exosomes. These ncRNAs, carried by exosomes, are involved in regulating various …